Immunotherapy of hematologic malignancies and metastatic solid tumors in experimental animals and man
| Autor: | Memet Aker, S. Slavin, Olga Gurevitch, Arnon Nagler, Reuven Or, T. Prighozina, M Y Shapira, S. Panighari |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Transplantation
Leukemia Bone marrow transplantation business.industry medicine.medical_treatment Graft vs Tumor Effect Hematopoietic Stem Cell Transplantation Graft vs Leukemia Effect Hematology Immunotherapy Haematopoiesis surgical procedures operative Neoplasms Immunology medicine Animals Humans Transplantation Homologous Neoplasm Metastasis Autogenous bone Stem cell business Bone Marrow Transplantation |
| Zdroj: | Bone Marrow Transplantation. 25:S54-S57 |
| ISSN: | 1476-5365 0268-3369 |
| Popis: | Following engraftment of donor hematopoietic cells and induction of host-versus-graft tolerance, immunocompetent lymphocytes of donor origin can induce graft-versus-leukemia (GVL) and graft-versus-tumor (GVT) effects. Engraftment of allogeneic bone marrow cells can be accomplished following non-myeloablative conditioning while possibly controlling graft-versus-host disease (GVHD). GVL and GVT effects may thus be successfully accomplished following non-myeloablative stem cell transplantation (NST) as shown by data derived from experimental animals and man. Bone Marrow Transplantation (2000) 25, Suppl. 25, S54–S57. |
| Databáze: | OpenAIRE |
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