Spatiotemporal spread of chikungunya virus in Sarawak, Malaysia
| Autor: | Rose Nani Mudin, Yoke Fun Chan, I-Ching Sam, Yvonne A. L. Lim, Sarat C. Dass, Wan Yusoff Wan Sulaiman, Balvinder Singh Gill, Romano Ngui, Chee Kheong Chong, Lokman Hakim Sulaiman |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
0301 basic medicine Range (biology) 030231 tropical medicine Population medicine.disease_cause Disease Outbreaks 03 medical and health sciences 0302 clinical medicine medicine Humans Chikungunya education Travel education.field_of_study Incidence (epidemiology) Malaysia Public Health Environmental and Occupational Health Outbreak General Medicine 030104 developmental biology Infectious Diseases Geography Georeference Chikungunya Fever Parasitology Rural area Chikungunya virus Basic reproduction number Cartography |
| Zdroj: | Transactions of The Royal Society of Tropical Medicine and Hygiene. 115:922-931 |
| ISSN: | 1878-3503 0035-9203 |
| DOI: | 10.1093/trstmh/trab053 |
| Popis: | Background We studied the spatiotemporal spread of a chikungunya virus (CHIKV) outbreak in Sarawak state, Malaysia, during 2009–2010. Methods The residential addresses of 3054 notified CHIKV cases in 2009–2010 were georeferenced onto a base map of Sarawak with spatial data of rivers and roads using R software. The spatiotemporal spread was determined and clusters were detected using the space-time scan statistic with SaTScan. Results Overall CHIKV incidence was 127 per 100 000 population (range, 0–1125 within districts). The average speed of spread was 70.1 km/wk, with a peak of 228 cases/wk and the basic reproduction number (R0) was 3.1. The highest age-specific incidence rate was 228 per 100 000 in adults aged 50–54 y. Significantly more cases (79.4%) lived in rural areas compared with the general population (46.2%, p Conclusions CHIKV initially spread quickly in rural areas mainly via roads, with lesser involvement of urban areas. Delayed spread occurred via river networks to more isolated areas in the rural interior. Understanding the patterns and timings of arboviral outbreak spread may allow targeted vector control measures at key transport hubs or in large transport vehicles. |
| Databáze: | OpenAIRE |
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