Capillary perfusion in skeletal muscle
| Autor: | Gregory K. Snyder, Caroline Farrelly, Joseph R. Coelho |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Male
Physiology Vastus lateralis muscle Diaphragm Muscle Smooth Vascular Microcirculation Physiology (medical) medicine.artery medicine Animals Fluorescent Dyes Soleus muscle Aorta Chemistry Muscles Skeletal muscle Rats Inbred Strains Anatomy musculoskeletal system Capillaries Rats Diaphragm (structural system) Perfusion medicine.anatomical_structure Organ Specificity Regional Blood Flow Circulatory system Cardiology and Cardiovascular Medicine |
| Zdroj: | American Journal of Physiology-Heart and Circulatory Physiology. 262:H828-H832 |
| ISSN: | 1522-1539 0363-6135 |
| DOI: | 10.1152/ajpheart.1992.262.3.h828 |
| Popis: | Timed perfusions of capillaries in soleus, vastus lateralis, and diaphragm of rats were determined by injecting a fluorescent dye into the aorta or right atrium. At preselected time intervals after dye injection, the circulation was interrupted, skeletal muscles were excised and frozen, and numerical counts of capillaries were made from transverse sections of the muscles. When fluorescent dye was injected into the right atrium or injected relatively slowly into the aorta, 100% of the capillaries contained dye by 3 s in vastus lateralis, 5 s in diaphragm, and 7 s in soleus. Rapid injection into the aorta delayed capillary filling. The rapid appearance of dye in skeletal muscle microvasculature suggests that either all capillaries are open to plasma flow all of the time or that the time constant for reopening of closed capillaries is very short. Furthermore, the patterns of capillary filling in skeletal muscle appear to be independent of muscle fiber type. |
| Databáze: | OpenAIRE |
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