| Autor: |
Martín, María Muñoz-San, Reverter, Gemma, Robles-Cedeño, Rene, Buxò, Maria, Ortega, Francisco José, Gómez, Imma, Tomàs-Roig, Jordi, Naiara Celarain, Villar, Luisa María, Perkal, Hector, Fernández-Real, José Manuel, Quintana, Ester, Lluís Ramió-Torrentà |
| Rok vydání: |
2019 |
| DOI: |
10.6084/m9.figshare.10310174.v1 |
| Popis: |
Additional file 1: Table S1. List of 28 analyzed miRNAs and percentage of detection for each miRNAs in CSF. Table S2. Validated targets for miR-21-5p, miR-146a-5p and miR-146b-5p from miRTarBase. Table S3. Differential miRNA expression between groups in plasma. Figure S1. TITLE: Receiver Operating Characteristics (ROC) analysis of individual (a-c) and combined (d) CSF miR-21, miR-146a and miR-146b to discriminate inflammatory activity. Figure S2. Correlation analysis of deregulated miRNAs and candidate targets mRNA expression in publicly available dataset. miRNA and mRNA expression profile of GSE28487 and GSE28490, respectively from Gene Expression Omnibus (GEO) DataSets (https://www.ncbi. nlm.nih.gov/gds/) was obtained. Scatter plots of correlations between upregulated miRNAs in CSF (miR-21, miR-146a and miR-146b) and their shared target genes (IRAK-1 and EGFR) were presented. rs: Rho Spearman; p: p value. Figure S3. Correlation of normalized Ct between CSF and plasma for (a) miR-21, (b) miR-146a and (c) miR-146b. Scatter plots showing the relationship between CSF and plasma levels for the deregulated miRNAs. rs: Rho Spearman; p: p value. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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