Electrophilic 18F from a Siemens 11 MeV proton-only cyclotron

Autor:	R.M. Adams, Gary J. Schrobilgen, Raman Chirakal, Gunter Firnau, G. Coates, E.S. Garnett
Rok vydání:	1995
Předmět:	Cancer Research Fluorine Radioisotopes Proton Chemistry Cyclotron Radiochemistry Cyclotrons law.invention Nuclear magnetic resonance law Yield (chemistry) Electrophile Molecular Medicine Radiology Nuclear Medicine and imaging Irradiation
Zdroj:	Nuclear medicine and biology. 22(1)
ISSN:	0969-8051
Popis:	Because more and more PET centres are using small proton cyclotrons there is a renewed interest in methods for the production of electrophilic 18F by proton irradiation of [18O]O2. A method for the routine production of clinically useful quantities of [18F]F2 having a specific activity of 35 Ci/mmol has been developed and implemented using an 11 MeV proton cyclotron and [18O]O2. Based on the yield, purity, reproducibility, and specific activity of [18F]F2 this is the most efficient method reported thus far.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0f297e7ddc2024f42e16e7433a867f https://pubmed.ncbi.nlm.nih.gov/7735160 Zobrazit plný text záznamu Full Text from ScienceDirect