A CASE OF GROWING TERATOMA SYNDROME
| Autor: | Toru Mashimo, Kyoko Baba, Hiroshi Matsui, Yasuhiro Shibata, Kazuhiro Suzuki, Junko Hirato, Sota Kurihara, Kazuto Ito, Keigo Okamura, Yoshitaka Sekine, Masahiro Nishii, Hidekazu Koike, Haruki Nakazato |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Urology medicine.medical_treatment 030232 urology & nephrology Metastasis Neoplasms Multiple Primary 03 medical and health sciences Retroperitoneal lymph node dissection 0302 clinical medicine Testicular Neoplasms medicine Humans Orchiectomy Stage (cooking) Neoplasm Staging Inguinal orchiectomy business.industry Teratoma Syndrome Seminoma medicine.disease Lymphatic Metastasis 030220 oncology & carcinogenesis Lymph Node Excision Immature teratoma alpha-Fetoproteins Lymph Tomography X-Ray Computed business Biomarkers |
| Zdroj: | The Japanese Journal of Urology. 107:115-120 |
| ISSN: | 1884-7110 0021-5287 |
| DOI: | 10.5980/jpnjurol.107.115 |
| Popis: | A 25-year-old man with a left testicular tumor underwent a high inguinal orchiectomy. Histopathological examination of the resected specimen revealed tumors of more than one histological type, mixed forms (seminoma, immature teratoma). Further evaluation revealed no metastasis (pT1N0M0S1 Stage IS).Four months after orchiectomy, alpha-fetoprotein (AFP) was elevated.CT scan revealed retroperitoneal masses of recurrent tumor. Although the AFP returned to normal level after four courses of BEP (bleomycin, etoposide and cisplatin), the retroperitoneal lymph nodes continued to grow. He underwent excision of the retroperitoneal lymph node dissection. Histopathological examination of the resected specimen revealed mature teratoma.Few reports examined about the development mechanism of growing teratoma syndrome (GTS). We considered that the development mechanism of GTS in this case is induction of differentiation. In this case report, we discuss the development mechanism of GTS based on bibliographical consideration. |
| Databáze: | OpenAIRE |
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