Intratendinous injection of platelet-rich plasma under US guidance to treat tendinopathy: a long-term pilot study
| Autor: | Lionel Pesquer, Jean Michel Serfaty, Alain Peuchant, Anne Perozziello, Philippe Loriaut, Alain Silvestre, Vincent Hummel, Marie Hélène Moreau Durieux, P Meyer, Patrick Boyer, Benjamin Dallaudière, E. Schouman-Claeys |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty WOMAC Visual analogue scale Tendinosis Osteoarthritis Platelet Transfusion Injections Intralesional medicine Humans Radiology Nuclear Medicine and imaging Ultrasonography Interventional business.industry Platelet-Rich Plasma Therapeutic effect medicine.disease Surgery Treatment Outcome Platelet-rich plasma Tendinopathy Female Cardiology and Cardiovascular Medicine business Hamstring |
| Zdroj: | Journal of vascular and interventional radiology : JVIR. 25(5) |
| ISSN: | 1535-7732 |
| Popis: | Purpose To assess the potential therapeutic effect of intratendinous injection of platelet-rich plasma (PRP) under ultrasound (US) guidance to treat tendon tears and tendinosis in a pilot study with long-term follow-up. Materials and Methods The study included 408 consecutive patients referred for treatment by PRP injection of tendinopathy in the upper (medial and lateral epicondylar tendons) and the lower (patellar, Achilles, hamstring and adductor longus, and peroneal tendons) limb who received a single intratendinous injection of PRP under US guidance. Clinical and US data were retrospectively collected for each anatomic compartment for upper and lower limbs before treatment (baseline) and 6 weeks after treatment. Late clinical data without US were collected until 32 months after the procedure (mean, 20.2 months). The McNemar test and regression model were used to compare clinical and US data. Results Quick DASH score, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, and residual US size of lesions were significantly lower after intratendinous injection of PRP under US guidance at 6 weeks and during long-term follow-up compared with baseline ( P P > .29). No clinical complication was reported during follow-up. Conclusions Intratendinous injection of PRP under US guidance appears to allow rapid tendon healing and is well tolerated. |
| Databáze: | OpenAIRE |
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