Association of kidney functions with a cascade of care for diabetes and hypertension in two geographically distinct Indian cohorts

Autor: Anil J Purty, Swasti Tiwari, Georgi Abraham, Mansi Bhardwaj, Sukhanshi Khandpur, Ashish Awasthi, Ariarathinam Newtonraj, Tripti Khanna
Rok vydání: 2021
Předmět:
Adult
Male
Adolescent
Endocrinology
Diabetes and Metabolism
Population
India
Renal function
030209 endocrinology & metabolism
Type 2 diabetes
Kidney
urologic and male genital diseases
Cohort Studies
Young Adult
03 medical and health sciences
0302 clinical medicine
Endocrinology
Risk Factors
Diabetes mellitus
Prevalence
Internal Medicine
Humans
Medicine
Diabetic Nephropathies
030212 general & internal medicine
Renal Insufficiency
Chronic
education
Socioeconomic status
education.field_of_study
Geography
business.industry
General Medicine
Middle Aged
Patient Acceptance of Health Care
medicine.disease
female genital diseases and pregnancy complications
medicine.anatomical_structure
Diabetes Mellitus
Type 2
Hypertension
Critical Pathways
Female
Residence
business
Delivery of Health Care
Glomerular Filtration Rate
Demography
Kidney disease
Zdroj: Diabetes Research and Clinical Practice. 176:108861
ISSN: 0168-8227
DOI: 10.1016/j.diabres.2021.108861
Popis: Aim Type 2 diabetes (T2DM) and hypertension (HTN) are the main modifiable risk factors of chronic kidney disease (CKD), among the known traditional and non-traditional risk factors. Methods We determined the prevalence and care-cascade of these modifiable CKD-risk factors and their association with socioeconomic status in adjoining Lucknow and Puducherry cities of India. Results 439 participants reported no CKD were recruited. Serum analysis revealed an Estimated Glomerular Filtration Rate (eGFR) ≥ 90 ml/min/1.73 m2 in 60.36% of the population. Of them, 55.85% had HTN and/or T2DM as CKD-risk factors; however, less than half of this population was unaware of their CKD-risk status. Awareness and treatment were significantly higher in Puducherry and were associated with literacy, occupation, and residence place. Although the CKD-risk population was about two times higher in Puducherry than Lucknow, the populations with mild-low eGFR were comparable in the two regions. Moreover, in Lucknow, mild-low eGFR and low awareness were more prevalent among the younger participants ( Conclusions Despite a higher prevalence of CKD-risk factors in Puducherry, populations with mild-low eGFR were comparable to Lucknow. More heightened awareness and better care cascade for CKD-risk factors in Puducherry may prevent or delay eGFR reduction.
Databáze: OpenAIRE
Externí odkaz: