Zone Electrophoresis of Cerebrospinal Fluid Proteins in Starch Gel

Autor:	Henn Kutt, James H. Pert
Rok vydání:	1958
Předmět:	Electrophoresis chemistry.chemical_compound Cerebrospinal fluid Biochemistry Chemistry Starch Cerebrospinal fluid proteins Cerebrospinal Fluid Proteins Blood proteins General Biochemistry Genetics and Molecular Biology Staining
Zdroj:	Experimental Biology and Medicine. 99:181-185
ISSN:	1535-3699 1535-3702
DOI:	10.3181/00379727-99-24288
Popis:	Summary1. A method for separation of cerebrospinal fluid proteins by electrophoresis in starch gel is presented, and its advantages and limitations are discussed. 2. In normal spinal fluid 10 to 12 protein fractions are observed. These correspond to serum proteins in the same individual but are present in different relative concentrations. In a number of cerebrospinal fluids from patients with neurologic diseases, considerable alterations of protein patterns were noted. Some examples of the type of abnormalities which may be encountered are illustrated. 3. In some of these pathologic specimens protein fractions were found, which we have not yet seen in serum or in normal spinal fluid. These have been designated as “fast gamma”and third and fourth prealbumins. 4. A method for concurrently staining lipoproteins in cerebrospinal fluid and serum has been described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeede164ebd2b571b64f21926286a5e5 https://doi.org/10.3181/00379727-99-24288 Zobrazit plný text záznamu