Significance of Suspected 'Chronic Aggressive Hepatitis' in Acute Hepatitis
| Autor: | Niels Tygstrup, Stig Asnaes, Torben Schiødt, Leo Ranek, Lis Fauerholdt |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Adult
Male medicine.medical_specialty Cirrhosis Hepatitis Viral Human Chronic liver disease Gastroenterology Hepatitis Internal medicine Biopsy medicine Humans Aged Hepatology medicine.diagnostic_test business.industry Chronic Active Incidence (epidemiology) Biopsy Needle Middle Aged Prognosis medicine.disease Liver Liver biopsy Acute Disease Chronic Disease Female business Viral hepatitis |
| Zdroj: | Gastroenterology. 73:543-548 |
| ISSN: | 0016-5085 |
| Popis: | Transition from acute to chronic hepatitis has important prognostic and therapeutic implications. In 17 patients with acute viral hepatitis, observed during a period of 7 years, a liver biopsy showed changes compatible with chronic aggressive hepatitis and superimposed acute hepatitis. Follow-up biopsies showed normal liver in 14 cases, chronic persistent hepatitis in 1, and cirrhosis in 2. In 12 cases the initial biopsy which showed changes suggestive of chronicity was taken 1 month after onset of symptoms of acute hepatitis, or later. Cases developing chronic liver disease showed no characteristic clinical, laboratory, or histological features at the time of the first biopsy. If the diagnosis of chronic active hepatitis is based on histological findings alone in patients with prolonged acute hepatitis, the incidence of this condition will be grossly overestimated. The transition from acute to chronic hepatitis cannot be recognized with any degree of certainty by presently available methods. |
| Databáze: | OpenAIRE |
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