Characteristics and outcomes of pregnant women with SARS-CoV-2 infection and other severe acute respiratory infections (SARI) in Brazil from January to November 2020
| Autor: | Joanna Merckx, Mariângela Freitas da Silveira, Deshayne B. Fell, Lisiane Freitas Leal, Natália Bordin Barbieri, Wanderson K Oliveira, Ricardo de Souza Kuchenbecker, Robert W. Platt, Angélica Espinosa Miranda, Lívia Antunes |
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| Rok vydání: | 2021 |
| Předmět: |
Maternal mortality
Microbiology (medical) Pediatrics medicine.medical_specialty Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Severe acute respiratory infections Infectious and parasitic diseases RC109-216 Microbiology Pregnancy Diabetes mellitus medicine Humans Respiratory system Pregnancy Complications Infectious Respiratory Tract Infections Respiratory tract infections business.industry SARS-CoV-2 COVID-19 medicine.disease Obesity QR1-502 Confidence interval Infectious Diseases Etiology Original Article Female Pregnant Women business SIVEP-Gripe Brazil |
| Zdroj: | Brazilian Journal of Infectious Diseases, Volume: 25, Issue: 5, Article number: 101620, Published: 29 NOV 2021 Brazilian Journal of Infectious Diseases v.25 n.5 2021 Brazilian Journal of Infectious Diseases Brazilian Society of Infectious Diseases (BSID) instacron:BSID Brazilian Journal of Infectious Diseases, Vol 25, Iss 5, Pp 101620-(2021) The Brazilian Journal of Infectious Diseases |
| ISSN: | 1678-4391 |
| Popis: | Background Knowledge about COVID-19 in pregnancy is limited, and evidence on the impact of the infection during pregnancy and postpartum is still emerging. Aim To analyze maternal morbidity and mortality due to severe acute respiratory infections (SARI), including COVID-19, in Brazil. Methods National surveillance data from the SIVEP-Gripe (Sistema de Informacao de Vigilância Epidemiologica da Gripe) was used to describe currently and recently pregnant women aged 10-49 years hospitalized for SARI from January through November, 2020. SARI cases were grouped into: COVID-19; influenza or other detected agent SARI; and SARI of unknown etiology. Characteristics, symptoms and outcomes were presented by SARI type and region. Binomial proportion and 95% confidence intervals (95% CI) for outcomes were obtained using the Clopper-Pearson method. Results Of 945,460 SARI cases in the SIVEP-Gripe, we selected 11,074 women aged 10–49 who were pregnant (7964) or recently pregnant (3110). COVID-19 was confirmed in 49.4% cases; 1.7% had influenza or another etiological agent; and 48.9% had SARI of unknown etiology. The pardo race/ethnic group accounted for 50% of SARI cases. Hypertension/Other cardiovascular diseases, chronic respiratory diseases, diabetes, and obesity were the most common comorbidities. A total of 362 women with COVID-19 (6.6%; 95%CI 6.0–7.3) died. Mortality was 4.7% (2.2–8.8) among influenza patients, and 3.3% (2.9–3.8) among those with SARI of unknown etiology. The South-East, Northeast and North regions recorded the highest frequencies of mortality among COVID-19 patients. Conclusion Mortality among pregnant and recently pregnant women with SARIs was elevated among those with COVID-19, particularly in regions where maternal mortality is already high. |
| Databáze: | OpenAIRE |
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