Hepatitis B and A markers in children with thalassaemia and sickle-cell disease in Riyadh
| Autor: | el-Hazmi Ma, Bahakim Hm, Babiker Ma |
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| Rok vydání: | 1986 |
| Předmět: |
Male
medicine.medical_specialty 030231 tropical medicine Cell Disease Anemia Sickle Cell Hepatitis A Antigens medicine.disease_cause Hepatitis B Antigens 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Internal medicine medicine Humans Hepatitis B e Antigens Hepatovirus Hepatitis B Antibodies Child Antigens Viral Hepatitis B virus Hepatitis B Surface Antigens business.industry Hepatitis A Transfusion Reaction Hepatitis B medicine.disease Hepatitis a virus Carrier rate medicine.anatomical_structure Child Preschool Immunoglobulin G Pediatrics Perinatology and Child Health Immunology Thalassemia Female High incidence business |
| Zdroj: | Annals of tropical paediatrics. 6(1) |
| ISSN: | 0272-4936 |
| Popis: | SUMMARYSera from 40 children with β-thalassaemia major, 54 children with sickle-cell disease and 120 matched controls were examined by radio-immunoassay for hepatitis B and A markers. The overall prevalence of hepatitis B virus markers was highest in children with thalassaemia followed by children with sickle-cell disease and lowest in the control group. The hepatitis A marker showed a reversed pattern, being lowest in the thalassaemic group. The high incidence of hepatitis B infection was presumably due to frequent blood transfusions, frequent exposure to hospital environment and the high carrier rate in the community. Frequent blood transfusions, however, seem to protect against hepatitis A virus infection. |
| Databáze: | OpenAIRE |
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