Follow-up of screening patients conservatively treated for cervical intraepithelial neoplasia grade 2–3
| Autor: | Patrizia Schincaglia, Lauro Bucchi, Paolo Cristiani, Pier Giorgio Dataro, Dino Davi, Maria De Nuzzo, L. Caprara, Marco Turci, Priscilla Sassoli de Bianchi, Silvano Costa, Franco Desiderio, Massimo Farneti, Marilena Manfredi, Carlo Naldoni, Fabio Falcini, N Collina, Sonia Prandi |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
medicine.medical_specialty Population Uterine Cervical Neoplasms Cervical intraepithelial neoplasia Treatment Refusal Humans Mass Screening Medicine Urban district education Mass screening Colposcopy education.field_of_study medicine.diagnostic_test business.industry Obstetrics and Gynecology Odds ratio Middle Aged Uterine Cervical Dysplasia medicine.disease Multinomial logistic regression analysis Surgery Treatment Outcome Italy Reproductive Medicine Female business Cervical Intraepithelial Neoplasia Grade 2/3 Follow-Up Studies |
| Zdroj: | European Journal of Obstetrics & Gynecology and Reproductive Biology. 133:227-231 |
| ISSN: | 0301-2115 |
| Popis: | Objectives To evaluate the frequency and correlates of non-adherence to follow-up among patients conservatively treated for CIN2-3. Study design Study population comprised 1560 patients aged 25–64 years from a screening programme in northern Italy. The regional standard protocol was used as a reference. Multinomial logistic regression analysis was used to estimate the odds ratio probability of a patient being lost to follow-up (no check-ups within 27 months of treatment) or incompletely followed-up (1–3 negative check-ups) versus having 4 negative check-ups. Results Three hundred twenty-six patients (21%) were lost to follow-up, 678 (43%) were incompletely followed-up, 352 (23%) presented for 4 negative check-ups and 204 (13%) were diagnosed with persistent disease. The probability of no or incomplete follow-up was greater for patients who lived in the urban district, who were treated in private settings (versus screening centres), who exhibited a visibile squamocolumnar junction on pre-treatment colposcopy, who were treated with cold knife excision and local destructive therapy (versus loop diathermy excision), and whose surgical specimens had positive excision margins. Conclusions Adherence to the reference protocol was poor. Factors involved in follow-up failures require greater clinical attention. |
| Databáze: | OpenAIRE |
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