Intramuscular Anti-D treatment for immune thrombocytopenia: A single centre experience

Autor: Sunil Lakhwani, Alberto López‐Las Heras, Pablo Rodríguez‐García, Sandra Iraheta, Taida Martín‐Santos, María José Rodríguez‐Salazar, Patricia Machado, Miguel‐Teodoro Hernández
Rok vydání: 2022
Předmět:
Zdroj: British journal of haematologyREFERENCES.
ISSN: 1365-2141
Popis: Intravenous Anti-Rhesus-D immunoglobulin (Anti-D) is a first-line treatment option for immune thrombocytopenia in non-splenectomised and RhD-positive patients. In this report, we retrospectively review our experience with intramuscular (IM) Anti-D treatment in 74 adult patients between 1990 and 2018. We found that 73% of patients showed a response; almost all of them had complete responses (68.89%), and 26% achieved complete responses sustained at least 6 months after treatment discontinuation. No significant side effects were observed with no cases of acute haemolysis or anaemia reported. We conclude from this study that IM Anti-D is an effective and safe treatment for immune thrombocytopenia.
Databáze: OpenAIRE