The Cupid shuffle: Do enhancers prefer specific promoters?

Autor:	Wang, Hsiao-Lin V., Corces, Victor G.
Rok vydání:	2022
Předmět:	Enhancer Elements Genetic Humans RNA Cell Biology Promoter Regions Genetic Molecular Biology Article Transcription Factors
Zdroj:	Mol Cell
ISSN:	1097-2765
Popis:	Two recent reports (Martinez-Ara et al., 2022; Bergman et al., 2022) explore the compatibility between enhancers and promoters and find that enhancers preferentially activate promoters with low intrinsic activity rather than favoring housekeeping or cell-type-specific promoters.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aede37c181fb32bd854bae8064e14320 https://doi.org/10.1016/j.molcel.2022.06.014 Zobrazit plný text záznamu