Felodipine-induced gingival hyperplasia: a clinical and histologic study

Autor: G. Fiore-Donno, Urs C. Belser, Roberto Di Felice, Tommaso Lombardi
Rok vydání: 1991
Předmět:
Zdroj: Journal of Oral Pathology and Medicine. 20:89-92
ISSN: 1600-0714
0904-2512
DOI: 10.1111/j.1600-0714.1991.tb00896.x
Popis: This paper reports, for the first time, gingival hyperplasia in a patient treated with felodipine, a drug which belongs to the group of calcium ion antagonists. The observed gingival overgrowth was most significant in the area of interdental papillae of the anterior region of the mouth. The described hyperplastic tissue was characterized by a firm and pale appearance, with a normally stippled pattern. Histopathologically, a conspicuous increase of fibrous connective tissue, as well as an inflammatory infiltrate and hyperplasia of the overlying epithelium were observed. Consequently, the present observation adds another drug to the list of substances capable to induce gingival hyperplasia.
Databáze: OpenAIRE