Pyogenic and Tuberculous Spondylodiskitis (Vertebral Osteomyelitis) in 80 Adult Patients
| Autor: | Z Behloul, Dominique Salmon-Ceron, M F Kahn, Jean-Louis Vildé, J. Saba, Christian Perronne, Catherine Leport |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Adult
Male Microbiology (medical) medicine.medical_specialty Discitis Tuberculosis medicine.disease_cause Gastroenterology Mycobacterium tuberculosis Streptococcal Infections Internal medicine Biopsy medicine Humans Vertebral osteomyelitis Blood culture Intervertebral Disc Aged Retrospective Studies Bacteriological Techniques medicine.diagnostic_test biology Streptococcus business.industry Biopsy Needle Osteomyelitis Middle Aged Staphylococcal Infections medicine.disease biology.organism_classification Surgery Infectious Diseases Female Tuberculosis Spinal Gram-Negative Bacterial Infections business Staphylococcus |
| Zdroj: | Clinical Infectious Diseases. 19:746-750 |
| ISSN: | 1537-6591 1058-4838 |
| Popis: | Bacterial spondylodiskitis--i.e., adjacent vertebral osteomyelitis and diskitis--was studied in 80 adult patients. The infection was due to Mycobacterium tuberculosis in 31 cases (39%) and to pyogenic bacteria in 49 cases (61%). The latter pathogens included gram-negative bacilli in 16 cases (20%), Staphylococcus species in 15 (19%), Streptococcus species in 9 (11%), and Corynebacterium species in 1 (1%); the pathogens in the 8 remaining cases (10%) were not identified. Of the patients with tuberculous spondylodiskitis, 55% came from countries where tuberculosis is endemic (P < .001). Cases due to staphylococci and those due to M. tuberculosis were associated with a high frequency of previous active infection with those respective organisms at any site (47% and 42%, respectively; P < .001) and with a high rate of neurological complications (33% and 32%, respectively; P < .001). Nine patients with pyogenic spondylodiskitis (18%) but only one patient with tuberculous spondylodiskitis (3%) had diabetes mellitus (P < .05). Blood cultures were positive in 23 (56%) of the 41 cases of pyogenic spondylodiskitis due to an identified bacterium. Discovertebral needle biopsy contributed to the bacteriologic diagnosis in 29 (74%) of 39 cases. |
| Databáze: | OpenAIRE |
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