A method for the determination of imipramine in human plasma by gas-liquid chromatography-mass fragmentography
| Autor: | Alberto Frigerio, E. Riva, Roberto Fanelli, Claudio Pantarotto, Paolo L. Morselli, F. De Nadai, Giorgio Belvedere |
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| Rok vydání: | 1972 |
| Předmět: |
Imipramine
Chromatography Gas Chromatography Chemistry Microchemistry Organic Chemistry Extraction (chemistry) General Medicine Mass spectrometry Biochemistry Mass Spectrometry Quantitative determination Mass fragmentography Analytical Chemistry Hexane chemistry.chemical_compound Human plasma Methods medicine Humans Gas chromatography Promazine medicine.drug |
| Zdroj: | Journal of Chromatography A. 74:201-208 |
| ISSN: | 0021-9673 |
| DOI: | 10.1016/s0021-9673(01)86150-1 |
| Popis: | A sensitive and specific method for the quantitative determination of imipramine in human biological fluids is described. After extraction with n -hexane, imipramine is detected by gas-liquid chromatography-mass fragmentography. The procedure permits routine analysis on relatively small amounts of plasma (1–2 ml) containing as little as 10 ng/ml of imipramine without any interference from endogenous substrates. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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