PLMaddon: a power-law module for the Matlab™ SBToolbox
| Autor: | Olaf Wolkenhauer, Cheng Sun, Julio Vera, Yvonne Oertel |
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| Rok vydání: | 2007 |
| Předmět: |
Statistics and Probability
Logarithm Computer science Models Biological Biochemistry Power law Computational science symbols.namesake Robustness (computer science) Taylor series Computer Simulation MATLAB Molecular Biology Simulation computer.programming_language Systems Biology Ode Computer Science Applications Computational Mathematics Computational Theory and Mathematics Ordinary differential equation symbols Programming Languages computer Algorithms Software |
| Zdroj: | Bioinformatics. 23:2638-2640 |
| ISSN: | 1367-4811 1367-4803 |
| Popis: | Summary: PLMaddon is a General Public License (GPL) software module designed to expand the current version of the SBToolbox (a Matlab ™ toolbox for systems biology; www.sbtoolbox.org) with a set of functions for the analysis of power-law models, a specific class of kinetic models, set in ordinary differential equations (ODE) and in which the kinetic orders can have positive/negative non-integer values. The module includes functions to generate power-law Taylor expansions of other ODE models (e.g. Michaelis-Menten type models), as well as algorithms to estimate steady-states. The robustness and sensitivity of the models can also be analysed and visualized by computing the power-law's logarithmic gains and sensitivities. Availability: PLMaddon is an open source module for the analysis of power-law models based on the SBToolbox. The latest version of PLMaddon is freely available from: www.sbi.uni-rostock.de/plmaddon The website contains a tutorial with examples, as well as an interactive introductory course on power-law models in systems biology. Contact: olaf.wolkenhauer@uni-rostock.de |
| Databáze: | OpenAIRE |
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