Anopheles moucheti and Anopheles vinckei are candidate vectors of ape Plasmodium parasites, including Plasmodium praefalciparum in Gabon
| Autor: | Patrick Durand, Nil Rahola, François Renaud, Julie Magnus, Benjamin Ollomo, Boris Makanga, Didier Fontenille, Franck Prugnolle, Christophe Paupy, Eric Willaume |
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| Přispěvatelé: | Diversity, ecology, evolution & Adaptation of arthropod vectors (MIVEGEC-DEEVA), Evolution des Systèmes Vectoriels (ESV), Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Centre International de Recherches Médicales de Franceville (CIRMF), Health, Emergence, Adaptation and Transmission (MIVEGEC-HEAT), Processus Écologiques et Évolutifs au sein des Communautés (PEEC), Parc of la Lékédi, Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]) |
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Evolutionary Genetics
Plasmodium [SDV]Life Sciences [q-bio] lcsh:Medicine Protozoology [SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics Phylogenetics and taxonomy Mosquitoes Polymerase Chain Reaction Animal Diseases 0302 clinical medicine Common species Zoonoses Plasmodium Vivax Malaria Falciparum lcsh:Science Phylogeny ComputingMilieux_MISCELLANEOUS 0303 health sciences Multidisciplinary biology Anopheles 3. Good health Infectious Diseases Medicine Female Research Article Mitochondrial DNA Pan troglodytes Plasmodium falciparum 030231 tropical medicine Zoology Microbiology DNA Mitochondrial Vector Biology 03 medical and health sciences Phylogenetics parasitic diseases Parasitic Diseases medicine Animals Humans [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology Gabon Biology 030304 developmental biology Evolutionary Biology Gorilla gorilla [SDV.BA.MVSA]Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health lcsh:R Tropical Diseases (Non-Neglected) Vectors and Hosts DNA Protozoan biology.organism_classification medicine.disease Virology Malaria Insect Vectors Vector (epidemiology) Parastic Protozoans lcsh:Q [SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis |
| Zdroj: | PLoS ONE, Vol 8, Iss 2, p e57294 (2013) PLoS ONE PLoS ONE, Public Library of Science, 2013, 8 (2), pp.e57294. ⟨10.1371/journal.pone.0057294⟩ PLoS ONE, 2013, 8 (2), pp.e57294. ⟨10.1371/journal.pone.0057294⟩ |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0057294⟩ |
| Popis: | During the last four years, knowledge about the diversity of Plasmodium species in African great apes has considerably increased. Several new species were described in chimpanzees and gorillas, and some species that were previously considered as strictly of human interest were found to be infecting African apes. The description in gorillas of P. praefalciparum, the closest relative of P. falciparum which is the main malignant agent of human malaria, definitively changed the way we understand the evolution and origin of P. falciparum. This parasite is now considered to have appeared recently, following a cross-species transfer from gorillas to humans. However, the Plasmodium vector mosquito species that have served as bridge between these two host species remain unknown. In order to identify the vectors that ensure ape Plasmodium transmission and evaluate the risk of transfer of these parasites to humans, we carried out a field study in Gabon to capture Anopheles in areas where wild and semi-wild ape populations live. We collected 1070 Anopheles females belonging to 15 species, among which An. carnevalei, An. moucheti and An. marshallii were the most common species. Using mtDNA-based PCR tools, we discovered that An. moucheti, a major human malaria vector in Central Africa, could also ensure the natural transmission of P. praefalciparum among great apes. We also showed that, together with An. vinckei, An. moucheti was infected with P. vivax-like parasites. An. moucheti constitutes, therefore, a major candidate for the transfer of Plasmodium parasites from apes to humans. |
| Databáze: | OpenAIRE |
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