Loss of Bone Mineral Density in Women Athletes During Aging
| Autor: | D. Elahi, Alice S. Ryan |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
musculoskeletal diseases Aging Greater trochanter medicine.medical_specialty Deoxypyridinoline Adolescent Endocrinology Diabetes and Metabolism Bone remodeling chemistry.chemical_compound Absorptiometry Photon Oxygen Consumption Endocrinology Bone Density Statistical significance Internal medicine Humans Medicine Orthopedics and Sports Medicine Femur Osteoporosis Postmenopausal Aged Femoral neck Bone mineral Lumbar Vertebrae biology Femur Neck business.industry Athletes musculoskeletal neural and ocular physiology Middle Aged musculoskeletal system biology.organism_classification Surgery medicine.anatomical_structure chemistry Body Composition Osteoporosis Regression Analysis Female business Biomarkers Sports |
| Zdroj: | Calcified Tissue International. 63:287-292 |
| ISSN: | 1432-0827 0171-967X |
| DOI: | 10.1007/s002239900528 |
| Popis: | Total and regional bone mineral density (BMD) by dual-energy-X-ray absorptiometry (DXA) and bone turnover were tested in 50 highly trained women athletes and 21 sedentary control women (18–69 years; BMI < 25 kg/m2). VO2max (ml · kg−1· min−1) and lean tissue mass (DXA) were significantly higher in the athletes versus controls (both P < 0.0001). Total body BMD did not decline significantly with age in the athletes whereas lumbar spine (L2–L4) BMD approached statistical significance (r =−0.26; P= 0.07). Significant losses of the femoral neck (r =− 0.42), Ward's triangle (r =−0.53), and greater trochanter BMD (r =−0.33; all P < 0.05) occurred with age in the athletes. In the athletes, total body BMD, L2–L4 BMD, and BMD of all sites of the femur were associated with lean tissue mass (r = 0.32 to r = 0.57, all P < 0.05) and VO2max (r = 0.29 to r = 0.48, all P < 0.05). Femoral neck and greater trochanter BMD were higher in the athletes than in controls (both P < 0.05) and lumbar spine and Ward's triangle BMD approached statistical significance (both P= 0.07). Bone turnover was assessed by serum bone-specific alkaline phosphatase (B-ALP), urinary deoxypyridinoline cross-links (Dpd), and urinary aminoterminal cross-linked telopeptides (NTX). There were no relationships between B-ALP or Dpd with age whereas NTX increased with age (r = 0.46, P < 0.05) in the entire group. Levels of B-ALP and NTX were negatively associated with total body, L2–L4, femoral neck, Ward's triangle, and greater trochanter BMD (P < 0.05). B-ALP and Dpd were not significantly different between athletes and controls whereas NTX was lower in the athletes than in controls (P < 0.001). The high levels of physical activity observed in women athletes increase aerobic capacity and improve muscle mass but are not sufficient to prevent the loss of bone with aging. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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