Impact of needle positioning on ablation success of irreversible electroporation: a unicentric retrospective analysis

Autor:	Ricardo Daniel da Florencia, Parham Tinoush, Boris Radeleff, Alexander Braun, Hans-Ulrich Kauczor, René Michael Mathy, De-Hua Chang, Omid Ghamarnejad
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Male Carcinoma Hepatocellular Cancer therapy Hepatocellular carcinoma medicine.medical_treatment Science Article 030218 nuclear medicine & medical imaging Lesion 03 medical and health sciences 0302 clinical medicine Retrospective analysis Humans Medicine In patient Aged Retrospective Studies Multidisciplinary Tumor size medicine.diagnostic_test business.industry Liver Neoplasms Magnetic resonance imaging Irreversible electroporation Middle Aged Ablation Magnetic Resonance Imaging Electroporation Outcomes research Needles 030220 oncology & carcinogenesis Liver cirrhosis Needle placement Cancer imaging Female medicine.symptom Nuclear medicine business
Zdroj:	Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020) Scientific Reports
ISSN:	2045-2322
Popis:	Irreversible electroporation (IRE) is an ablation procedure in which cell death is induced by ultrashort electrical pulses. In this unicentric retrospective study we investigated the influence of needle positioning on ablation success. 15 IREs with residual tumor after ablation, detected in the first follow-up MRI, were included, and compared with 30 successful ablations. Evaluation of needle geometry revealed significantly higher values for needle divergence (NDiv, 7.0° vs. 3.7°, p = 0.02), tumor-center-to-ablation-center distance (TACD, 11.6 vs. 3.2 mm, p p = 0.04), and tumor diameter per needle (7.5 vs. 5.9 mm/needle, p = 0.01) in patients with residual tumor. The average number of needles used was higher in the group without residual tumor after ablation (3.1 vs. 2.4, p = 0.04). In many cases with residual tumor, needle depth was too short (2.1 vs. 6.8 mm tumor overlap beyond the most proximal needle tip, p p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb59932204554118d6a833c62d46fee https://doaj.org/article/726babb3cbe449219b5b57f093aa6e20 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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