Verrucous Carcinoma of the Vulva Associated With an Unusual Type 6 Human Papillomavirus
| Autor: | Jenson Ab, Lancaster Wd, Hunt J, Rando Rf, Sedlacek Tv, Kurman Rj |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Adult
Genetic Markers viruses Genome Virus DNA sequencing medicine Humans Cloning Molecular Papillomaviridae Genomic organization Vulvar neoplasm Vulvar Neoplasms biology Verrucous carcinoma virus diseases Obstetrics and Gynecology DNA Restriction Enzymes biology.organism_classification medicine.disease Virology Carcinoma Papillary Vulvar Verrucous Carcinoma Tumor Virus Infections Condylomata Acuminata Female |
| Zdroj: | Obstetrics & Gynecology. 67:70S-75S |
| ISSN: | 0029-7844 |
| DOI: | 10.1097/00006250-198603001-00021 |
| Popis: | An unusually rapid growing vulvar verrucous carcinoma found associated with human papillomavirus type 6 is described. Both human papillomavirus structural antigens and deoxyribonucleic acid (DNA) sequences were detected in the tumor biopsy. The human papillomavirus genome was isolated and compared with the genome of human papillomavirus type 6b, which was cloned from an anogenital wart. The two genomes were extremely homologous in genomic organization and DNA sequence, except for a region on the viral genome containing the virus control elements. A discussion of this observation and how it could relate to the importance of viral subtypes follows. |
| Databáze: | OpenAIRE |
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