Quality control and evaluation of plant epigenomics data
Autor: | Xuemei Chen, Franziska Turck, Molly Megraw, Rebecca A. Mosher, Xuehua Zhong, Xuan Zhang, Siobhan M. Brady, Alexandre P. Marand, Blake C. Meyers, Michael J. Axtell, Robert J. Schmitz |
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Rok vydání: | 2021 |
Předmět: |
Epigenomics
Quality Control Regular Issue AcademicSubjects/SCI01280 media_common.quotation_subject Genomics Plant Science Computational biology Biology Regulatory Sequences Nucleic Acid Genome Quality (business) media_common AcademicSubjects/SCI01270 AcademicSubjects/SCI02288 AcademicSubjects/SCI02287 AcademicSubjects/SCI02286 Cell Biology Repetitive Regions Plants Chromatin Data quality Commentary Transcription (software) Genome Plant |
Zdroj: | The Plant Cell |
ISSN: | 1532-298X |
Popis: | Epigenomics is the study of molecular signatures associated with discrete regions within genomes, many of which are important for a wide range of nuclear processes. The ability to profile the epigenomic landscape associated with genes, repetitive regions, transposons, transcription, differential expression, cis-regulatory elements, and 3D chromatin interactions has vastly improved our understanding of plant genomes. However, many epigenomic and single-cell genomic assays are challenging to perform in plants, leading to a wide range of data quality issues; thus, the data require rigorous evaluation prior to downstream analyses and interpretation. In this commentary, we provide considerations for the evaluation of plant epigenomics and single-cell genomics data quality with the aim of improving the quality and utility of studies using those data across diverse plant species. Useful consideration for quality control and evaluation of plant epigenomics data are provided. |
Databáze: | OpenAIRE |
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