Measurement of cortisol and lymphocyte subpopulations in depressed and conduct-disordered adolescents

Autor: Lois E. Marshall, Steven D. Targum, Kelly Magac-Harris, Robert G. Skwerer, Lindsay L. Clarkson
Rok vydání: 1990
Předmět:
Zdroj: Journal of affective disorders. 18(2)
ISSN: 0165-0327
Popis: Lymphocyte subpopulations were analyzed in 11 adolescents with major depressive disorder, 11 with conduct disorder, and eight normal age-matched subjects. No significant differences were noted on any T or B cell measure between the groups. Further, no significant correlations were found between any cortisol measure (baseline cortisol, post-dexamethasone cortisol, urinary free cortisol) and any lymphocyte measure in either depressed or conduct-disordered adolescents. The negative findings in this small sample contrast with those reported in adult patients and suggest that an aging effect may be associated with the immunological changes reported in older depressed patients.
Databáze: OpenAIRE