Acute toxicity assessment of arsenic, chromium and almix 20WP in Euphlyctis cyanophlyctis tadpoles
| Autor: | Aloke Kumar Mukherjee, Apurba Ratan Ghosh, Palas Samanta, Sandipan Pal |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Chromium
Health Toxicology and Mutagenesis 0211 other engineering and technologies chemistry.chemical_element 02 engineering and technology 010501 environmental sciences 01 natural sciences Aquatic toxicology Arsenic chemistry.chemical_compound Animal science Toxicity Tests Acute Animals 0105 earth and related environmental sciences Glutathione Transferase 021110 strategic defence & security studies biology Herbicides Public Health Environmental and Occupational Health General Medicine Glutathione biology.organism_classification Alkaline Phosphatase Pollution Acute toxicity Glutathione S-transferase chemistry Larva Toxicity biology.protein Alkaline phosphatase Euphlyctis cyanophlyctis Anura Water Pollutants Chemical |
| Zdroj: | Ecotoxicology and environmental safety. 191 |
| ISSN: | 1090-2414 |
| Popis: | Heavy metals and herbicide are gaining serious environmental concern in aquatic toxicology due to its adverse effects on aquatic organisms especially amphibians. Accordingly, present study first time evaluated the acute toxicity of two heavy metals [arsenic (As3+) and chromium (Cr6+)] and a herbicide (Almix) to Indian skittering frog tadpole, Euphlyctis cyanophlyctis. The LC50 values of As, Cr and Almix for 24, 48, 72 and 96 h were 73.58, 56.31, 43.58 and 32.58 mg L−1; 326.68, 224.31, 171.92 and 141.99 mg L−1; and 1297.85, 1148.22, 1033.62 and 955.17 mg L−1, respectively. It also revealed the concentration- and time-dependent increased mortality rate under these toxicants. The safety concentrations (SC) of As, Cr and Almix to tadpoles were 3.26, 14.20 and 95.52 mg L−1, respectively. The findings disclosed that As is highly toxic to E. cyanophlyctis than Cr and Almix. Alkaline phosphatase (ALP) activity showed varied responses to exposed chemicals. In particularly, ALP activity reduced significantly for Cr treatment. Glutathione S-transferase (GST) activity in E. cyanophlyctis was significantly inhibited by As treatment (p 0.05). The As toxicity correlates positively with GST inhibition (r = 0.779, p 0.05). This result indicated that GST play a crucial role for regulating the tadpole mortality and intoxication by As, Cr and Almix. Overall, our findings demonstrate the different levels of toxic sensitivity (adverse effects) under different toxicants on E. cyanophlyctis tadpoles. Finally, the present findings could be used as baseline information of toxicosis for metalloid, heavy metal and herbicide exposures in wild frog populations. |
| Databáze: | OpenAIRE |
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