Prevalence of Trypanosoma cruzi and Leishmania chagasi infection and risk factors in a Colombian indigenous population
| Autor: | S Duque Beltran, Luis E. Gualdrón, A Corredor Arjona, P Reyes, María Mercedes Santacruz, M Bueno, Elvia Cáceres, Myriam Consuelo López, C A Alvarez Moreno, Carlos A. Agudelo |
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| Jazyk: | angličtina |
| Rok vydání: | 1999 |
| Předmět: |
Chagas’ disease
Adult Chagas disease lcsh:Arctic medicine. Tropical medicine lcsh:RC955-962 Trypanosoma cruzi RC955-962 Population Seroprevalence Disease Vectors Colombia Sensitivity and Specificity Dogs Risk Factors Seroepidemiologic Studies Arctic medicine. Tropical medicine parasitic diseases medicine Animals Humans Chagas Disease education Aged Leishmania Visceral leishmaniasis education.field_of_study biology Leishmaniasis General Medicine Leishmania chagasi Middle Aged medicine.disease biology.organism_classification Chagas? disease Infectious Diseases Immunology Housing Leishmaniasis Visceral |
| Zdroj: | Revista do Instituto de Medicina Tropical de São Paulo, Vol 41, Iss 4, Pp 229-234 (1999) Scopus-Elsevier Revista do Instituto de Medicina Tropical de São Paulo, Volume: 41, Issue: 4, Pages: 229-234, Published: JUL 1999 |
| ISSN: | 1678-9946 0036-4665 |
| Popis: | This study was carried out in order to obtain base-line data concerning the epidemiology of American Visceral Leishmaniasis and Chagas’ Disease in an indigenous population with whom the government is starting a dwelling improvement programme. Information was collected from 242 dwellings (1,440 people), by means of house to house interviews about socio-economic and environmental factors associated with Leishmania chagasi and Trypanosoma cruzi transmission risk. A leishmanin skin test was applied to 385 people and 454 blood samples were collected on filter paper in order to detect L. chagasi antibodies by ELISA and IFAT and T. cruzi antibodies by ELISA. T. cruzi seroprevalence was 8.7% by ELISA, L. chagasi was 4.6% and 5.1% by IFAT and ELISA, respectively. ELISA sensitivity and specificity for L. chagasi antibodies were 57% and 97.5% respectively, as compared to the IFAT. Leishmanin skin test positivity was 19%. L. chagasi infection prevalence, being defined as a positive result in the three-immunodiagnostic tests, was 17.1%. Additionally, 2.7% of the population studied was positive to both L. chagasi and T. cruzi, showing a possible cross-reaction. L. chagasi and T. cruzi seropositivity increased with age, while no association with gender was observed. Age (p |
| Databáze: | OpenAIRE |
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