| Autor: |
Jian Li, Heng Li Chee, Yi Ting Chong, Benjamin Qi Yu Chan, Kun Xue, Poh Chong Lim, Xian Jun Loh, FuKe Wang |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
ACS applied materialsinterfaces. |
| ISSN: |
1944-8252 |
| Popis: |
Hydrogels have become popular in biomedical applications, but their applications in muscle and tendon-like bioactuators have been hindered by low toughness and elastic modulus. Recently, a significant toughness enhancement of a single hydrogel network has been successfully achieved by the Hofmeister effect. However, little has been conducted for the Hofmeister effect on the hybrid hydrogels, although they have a special network structure consisting of two types of polymer components. Herein we fabricated hybrid poly(2-hydroxyethyl methacrylate) (PHEMA)-gelatin hydrogels with high mechanical performance and stimuli response. An ideal bicontinuous phase separation structure of the PHEMA (rigid) and gelatin (ductile) was observed with embedded microdisc-like gelatin in the three-dimensional polymeric network of PHEMA. A significant enhancement of mechanical performance by the Hofmeister effect was attributed to the salting-out-induced stronger and closer interphase interaction between PHEMA and gelatin. A superior comprehensive mechanical performance with fracture elongation over 650%, tensile strength of 5.2 MPa, toughness of 13.5 MJ/m |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
