Evolutionary Changes in the Content of Dehydrogenase System Metabolites as a Mechanism of Adaptation to Cold in Higher Vertebrates
| Autor: | O N Kolosova, N.G. Solomonov, B. M. Kershengolts |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Hibernation Acclimatization Aldehyde dehydrogenase Rodentia Dehydrogenase General Biochemistry Genetics and Molecular Biology 03 medical and health sciences chemistry.chemical_compound Animals Humans Horses Alcohol dehydrogenase Ethanol 030102 biochemistry & molecular biology General Immunology and Microbiology biology Alcohol Dehydrogenase Acetaldehyde General Medicine Aldehyde Dehydrogenase Biological Evolution Cold Temperature Liver Biochemistry chemistry biology.protein Adaptation General Agricultural and Biological Sciences |
| Zdroj: | Doklady Biological Sciences. 482:170-173 |
| ISSN: | 1608-3105 0012-4966 |
| Popis: | It has been found that the optimal body balance control under the conditions of the adaptation to cold is mostly determined by the ratio of the blood concentrations of endogenous ethanol and acetaldehyde related to the activities of liver alcohol dehydrogenase and aldehyde dehydrogenase in the order of increasing level of adaptation: higher vertebrates unadapted to cold, including human → small animals adapted to cold → large animals adapted to cold native to the North → hibernators, regardless of the species specificity and the environment. |
| Databáze: | OpenAIRE |
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