Sesquarterpenes (C35 terpenes) biosynthesized via the cyclization of a linear C35 isoprenoid by a tetraprenyl-β-curcumene synthase and a tetraprenyl-β-curcumene cyclase: identification of a new terpene cyclase
| Autor: | Hiroko Hoshino, Mizuki Tanno, Mami Nakajima, Tsutomu Sato, Tsutomu Hoshino, Satoru Yoshida |
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| Rok vydání: | 2011 |
| Předmět: |
chemistry.chemical_classification
Curcumin ATP synthase biology Chemistry Terpenes General Chemistry Bacillus subtilis biology.organism_classification Biochemistry Cyclase Catalysis Terpenoid Enzymes Terpene Colloid and Surface Chemistry Sequence homology Enzyme Cyclization Terpene synthase N terminal domain biology.protein |
| Zdroj: | Journal of the American Chemical Society. 133(25) |
| ISSN: | 1520-5126 |
| Popis: | In this study, mono- and pentacyclic C(35) terpenes from Bacillus subtilis were biosynthesized via the cyclization of C(35) isoprenoid using purified enzymes, including the first identified new terpene cyclase that shows no sequence homology to any of the known terpene cyclases. On the basis of these findings, we propose that these C(35) terpenes should be called the new family of "sesquarterpenes." |
| Databáze: | OpenAIRE |
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