Carcinoma of the bronchus in the Yorkshire region of England 1976-1990: trends since 1984
| Autor: | C. F. Johnston, M. F. Muers, P. L. Rider, Andrew D. M. Smith, C. K. Connolly, S. M. Crawford |
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| Rok vydání: | 1997 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Lung Neoplasms Adenocarcinoma Internal medicine medicine Carcinoma Humans Carcinoma Small Cell Lung cancer Survival rate Aged Bronchus business.industry Respiratory disease Middle Aged medicine.disease Cancer registry Surgery Survival Rate Carcinoma Bronchogenic medicine.anatomical_structure England Quartile Carcinoma Squamous Cell Female business |
| Zdroj: | European Respiratory Journal. 10:397-403 |
| ISSN: | 1399-3003 0903-1936 |
| DOI: | 10.1183/09031936.97.10020397 |
| Popis: | We wished to confirm that, in patients with lung cancer, trends in demography and histology, together with modest improvements in survival, first seen in the 1976-1983 cohorts, continued to 1990. All lung cancer patients resident in Yorkshire are notified to the Cancer Registry, whose database was analysed for this report. A total of 38,275 patients were notified. There was no change in annual notification for males but an increase from 513 to 815 annual notifications in females between 1976 and 1990. Mean age increased by 3 yrs, in males to 67.4 yrs and in females to 67.2 yrs. Histological confirmation rate increased from 43% to 60% (mean age from 60.8 to 64.5 yrs). Annual notifications of adenocarcinoma increased consistently from 108 to 253. Two year surgical survival improved from 37.4 to 44.3%, doubling in subjects aged > or = 70 yrs to 43.8%. Over the 15 year period, there was no improvement in survival aged < 60 yrs, but a significant improvement in the 60-69 and > or = 70 yrs age groups. Analysis of survival by quartiles showed significant improvement at all levels (first interval 20 to 24 days, median 79 to 91 days, third interval 224 to 266 days). The modest improvement in outlook was confirmed, confined to older subjects after 1983, and partially masked by increasing age. Survival after surgery is now independent of age. |
| Databáze: | OpenAIRE |
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