A Handheld Metabolic Device (Lumen) to Measure Fuel Utilization in Healthy Young Adults: Device Validation Study
| Autor: | James R. Bagley, Shlomo Yeshurun, Kent A. Lorenz, Merav Mor, Marialice Kern, Richard Aziz, Julissa Ortiz-Delatorre |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Cart medicine.medical_specialty Validation study fuel utilization ParvoMedics TrueOne 2400 Computer applications to medicine. Medical informatics R858-859.7 Lumen (anatomy) 030209 endocrinology & metabolism lung 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Medical technology Young adult R855-855.5 Respiratory exchange ratio resting metabolic rate validation indirect calorimetry Original Paper breath business.industry respiratory exchange ratio respiratory testing 030104 developmental biology Basal metabolic rate Cardiology Breathing Lumen young adult measurement business Glucose intake metabolism |
| Zdroj: | Interactive Journal of Medical Research Interactive Journal of Medical Research, Vol 10, Iss 2, p e25371 (2021) |
| ISSN: | 1929-073X |
| Popis: | Background Metabolic carts measure the carbon dioxide (CO2) produced and oxygen consumed by an individual when breathing to assess metabolic fuel usage (carbohydrates versus fats). However, these systems are expensive, time-consuming, and only available in health care laboratory settings. A small handheld device capable of determining metabolic fuel usage via CO2 from exhaled air has been developed. Objective The aim of this study is to evaluate the validity of a novel handheld device (Lumen) for measuring metabolic fuel utilization in healthy young adults. Methods Metabolic fuel usage was assessed in healthy participants (n=33; mean age 23.1 years, SD 3.9 years) via respiratory exchange ratio (RER) values obtained from a metabolic cart as well as % CO2 from the Lumen device. Measurements were performed at rest in two conditions: fasting, and after consuming 150 grams of glucose, in order to determine changes in metabolic fuel usage. Reduced major axis regression and simple linear regression were performed to test for agreement between RER and Lumen % CO2. Results Both RER and Lumen % CO2 significantly increased after glucose intake (P Conclusions This study shows the validity of Lumen for detecting changes in metabolic fuel utilization in a comparable manner with a laboratory standard metabolic cart, providing the ability for real-time metabolic information for users under any circumstances. |
| Databáze: | OpenAIRE |
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