The Burden in Caregivers of Multiple Myeloma Patients Undergoing Outpatient Autologous Stem-Cell Transplantation Compared to Inpatient Transplantation
| Autor: | Salvatore Gallo, Antonio Maria Rossetti, Lucrezia Imbalzano, Graziella D'Arrigo, Annalisa Paviglianiti, Tiziana Gangemi, Massimo Martino, Valentina Romeo, Gaetana Porto, Nicola Meliambro, Domenico Porcino, Mercedes Gori, Giuseppe Console, Letteria Russo, Giovanni Tripepi, Annalisa Pitino, Pasquale Fabio Provenzano, Giuseppa Cusumano |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Activities of daily living Family support Transplantation Autologous 03 medical and health sciences Young Adult 0302 clinical medicine Autologous stem-cell transplantation Quality of life Internal medicine medicine Humans Disease burden Multiple myeloma Aged business.industry Hematopoietic Stem Cell Transplantation Hematology Middle Aged medicine.disease Transplantation Systematic review Oncology Ambulatory Surgical Procedures Caregivers 030220 oncology & carcinogenesis Quality of Life Female business Multiple Myeloma 030215 immunology |
| Zdroj: | Clinical lymphoma, myelomaleukemia. 21(4) |
| ISSN: | 2152-2669 |
| Popis: | Background The application of different models of autologous stem-cell transplantation (ASCT) in multiple myeloma has demonstrated the feasibility and safety of outpatient-based programs of care. Although several systematic reviews have evaluated the burden of caregivers, only a few studies have included outpatient ASCT. Patients and Methods The feelings of lack of family support, daily activities, and general health were compared between caregivers of 2 groups of patients with multiple myeloma who underwent inpatient (n = 71) or outpatient (n = 25) ASCT. Results The 3 features did not significantly differ between the 2 study groups at baseline, before, and 3 months after ASCT. Multivariate modeling showed that the baseline values were significantly related to the changes in study outcomes independent of patient and caregiver characteristics. Other correlates were caregivers’ work and patient age for impact on daily activities and disease burden across time for impact on general health (all P Conclusion The outpatient model neither improves nor impairs global caregivers’ burden compared to standard ASCT care. Further research is needed to confirm this observation and to better assess the burden and quality of life of caregivers and their influence on patient outcomes and quality of life. |
| Databáze: | OpenAIRE |
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