Associations Between General and Abdominal Adiposity and Mortality in Individuals With Diabetes Mellitus
| Autor: | Joline W.J. Beulens, Kim Overvad, Benedetta Bendinelli, Daphne L. van der A, Jukka Montonen, Bo Hedblad, Olov Rolandsson, Paul W. Franks, Peter M. Nilsson, Amalia Mattiello, Ute Nöthlings, Birgit Teucher, Carlotta Sacerdote, Sara Grioni, Tina Landsvig Berentzen, Eva Ardanaz, Tobias Pischon, Anne Tjønneland, Rudolf Kaaks, Heiner Boeing, Annemieke M.W. Spijkerman, Yvonne T. van der Schouw, Jytte Halkjær, Rosario Tumino, L. Arriola, Diewertje Sluik |
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| Přispěvatelé: | Epidemiology and Data Science, ACS - Diabetes & metabolism, ACS - Heart failure & arrhythmias, APH - Health Behaviors & Chronic Diseases |
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Waist Epidemiology Abdominal Fat Body Mass Index Cohort Studies Diabetes Complications Waist–hip ratio Risk Factors Internal medicine Diabetes mellitus Surveys and Questionnaires medicine Confidence Intervals Diabetes Mellitus Odds Ratio Prevalence Humans Life Style Abdominal obesity Aged Proportional Hazards Models Waist-to-height ratio business.industry Waist-Hip Ratio Odds ratio Middle Aged medicine.disease Obesity Body Height Europe Endocrinology Diabetes Mellitus Type 2 Obesity Abdominal Multivariate Analysis Female medicine.symptom Waist Circumference business Body mass index |
| Zdroj: | Sluik, D, Boeing, H, Montonen, J, Pischon, T, Kaaks, R, Teucher, B, Tjønneland, A, Halkjaer, J, Berentzen, T L, Overvad, K, Arriola, L, Ardanaz, E, Bendinelli, B, Grioni, S, Tumino, R, Sacerdote, C, Mattiello, A, Spijkerman, A M W, van der A, D L, Beulens, J W, van der Schouw, Y T, Nilsson, P M, Hedblad, B, Rolandsson, O, Franks, P W & Nöthlings, U 2011, ' Associations Between General and Abdominal Adiposity and Mortality in Individuals With Diabetes Mellitus ', American Journal of Epidemiology, vol. 174, no. 1, pp. 22-34 . https://doi.org/10.1093/aje/kwr048 American Journal of Epidemiology, 174(1), 22-34. Oxford University Press Sluik, D, Boeing, H, Montonen, J, Pischon, T, Kaaks, R, Teucher, B, Tjønneland, A, Halkjaer, J, Berentzen, T L, Overvad, K, Arriola, L, Ardanaz, E, Bendinelli, B, Grioni, S, Tumino, R, Sacerdote, C, Mattiello, A, Spijkerman, A M W, Van Der A, D L, Beulens, J W, Van Der Schouw, Y T, Nilsson, P M, Hedblad, B, Rolandsson, O, Franks, P W & Nöthlings, U 2011, ' Associations between general and abdominal adiposity and mortality in individuals with diabetes mellitus ', American Journal of Epidemiology, vol. 174, no. 1, pp. 22-34 . https://doi.org/10.1093/aje/kwr048 |
| ISSN: | 1992-2000 0002-9262 |
| Popis: | Individuals with diabetes mellitus are advised to achieve a healthy weight to prevent complications. However, fat mass distribution has hardly been investigated as a risk factor for diabetes complications. The authors studied associations between body mass index, waist circumference, waist/hip ratio, and waist/height ratio and mortality among individuals with diabetes mellitus. Within the European Prospective Investigation into Cancer and Nutrition, a subcohort was defined as 5,435 individuals with a confirmed self-report of diabetes mellitus at baseline in 1992-2000. Participants were aged 57.3 (standard deviation, 6.3) years, 54% were men, the median diabetes duration was 4.6 (interquartile range, 2.0-9.8) years, and 22% of the participants used insulin. Body mass index, as indicator of general obesity, was not associated with higher mortality, whereas all measurements of abdominal obesity showed a positive association. Associations generally were slightly weaker in women. The strongest association was observed for waist/height ratio: In the fifth quintile, the hazard rate ratio was 1.88 (95% confidence interval: 1.33, 2.65) for men and 2.46 (95% confidence interval: 1.46, 4.14) for women. Measurements of abdominal, but not general, adiposity were associated with higher mortality in diabetic individuals. The waist/height ratio showed the strongest association. Respective indicators might be investigated in risk prediction models. |
| Databáze: | OpenAIRE |
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