A multidisciplinary approach for the treatment of GIST liver metastasis
| Autor: | Thomas W. Mesko, Juan C. Paramo, Pejman Radkani, Marcelo M. Ghersi |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Gastrointestinal Stromal Tumors medicine.medical_treatment lcsh:Surgery Case Report lcsh:RC254-282 Piperazines Metastasis Surgical oncology medicine Humans Combined Modality Therapy neoplasms Aged GiST business.industry Liver Neoplasms Imatinib lcsh:RD1-811 Bowel resection Perioperative Jaundice lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease Embolization Therapeutic digestive system diseases Pyrimidines Oncology Benzamides Imatinib Mesylate Female Surgery Radiology medicine.symptom business medicine.drug |
| Zdroj: | World Journal of Surgical Oncology, Vol 6, Iss 1, p 46 (2008) World Journal of Surgical Oncology |
| ISSN: | 1477-7819 |
| DOI: | 10.1186/1477-7819-6-46 |
| Popis: | Background Advanced gastrointestinal stromal tumors (GISTs) can metastasize and recur after a long remission period, resulting in serious morbidity, mortality, and complex management issues. Case presentation A 67-year-old woman presented with epigastric fullness, mild jaundice and weight loss with a history of a bowel resection 7 years prior for a primary GIST of the small bowel. The finding of a heterogeneous mass 15.5 cm in diameter replacing most of the left lobe of the liver by ultrasonography and CT, followed by positive cytological studies revealed a metastatic GIST. Perioperative optimization of the patient's nutritional status along with biliary drainage, and portal vein embolization were performed. Imatinib was successful in reducing the tumor size and facilitating surgical resection. Conclusion A well-planned multidisciplinary approach should be part of the standard management of advanced or metastatic GIST. |
| Databáze: | OpenAIRE |
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