The auditory event-related potential is a stable and reliable measure in elderly subjects over a 3 year period
| Autor: | Julie V Patterson, Curt A. Sandman |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Male
medicine.medical_specialty Aging Time Factors Electrodiagnosis genetic structures Auditory event Electroencephalography Audiology Medical and Health Sciences Developmental psychology event-related potential Engineering Event-related potential Physiology (medical) medicine Humans Reliability (statistics) Aged Aged 80 and over reliability Neurology & Neurosurgery medicine.diagnostic_test Psychology and Cognitive Sciences Reproducibility of Results Mean age stability Middle Aged Sensory Systems Neurology Evoked Potentials Auditory Female Neurology (clinical) Psychology psychological phenomena and processes |
| Zdroj: | Sandman, CA; & Patterson, JV. (2000). The auditory event-related potential is a stable and reliable measure in elderly subjects over a 3 year period.. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 111(8), 1427-1437. doi: 10.1016/s1388-2457(00)00320-5. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/0wk574wh |
| ISSN: | 1388-2457 |
| DOI: | 10.1016/s1388-2457(00)00320-5. |
| Popis: | Objectives : Valid markers of psychobiological processes, including changes over the lifespan, must be reliable. This study investigated the reliability of the auditory event-related potential (ERP) over a 3 year period. Methods : Predictable and unpredictable rare tones were embedded in common-to-rare sequences at 3 different ratios (2:3, 2:5 and 2:8). Forty-six older (mean age 72.3 years) volunteers pressed a key to the rare tones, and ERPs (Fz, Cz and Pz) and reaction time (RT) were measured. Reliability across years was assessed using 3 methods: (1) determination of the stability of waveform components (P1, N1, P2, N2 and P3); (2) cross-correlation of successive 15 ms epochs of within-subject ERPs; and (3) cross-correlation of 15 ms epochs of between-subject ERPs. Results : With all analyses, the ERP was stable. Analysis of the scored components indicated that P3 was especially stable in the unpredictable rare (2:8) condition. Earlier components were equally stable across all conditions. Analysis of 15 ms ERP epochs indicated significant ERP stability 60 ms after stimulation, lasting over 640 ms. Conclusions : Robust within-subject reliability of the ERP strengthens its potential use for detecting preclinical changes in at-risk elderly populations. |
| Databáze: | OpenAIRE |
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