Electrocardiographic spatial loops indicate organization of atrial fibrillation minutes before ablation-related transitions to atrial tachycardia
| Autor: | Rishi Trikha, Sanjiv M. Narayan, Paul J. Wang, David E. Krummen, Junaid A.B. Zaman, Tina Baykaner |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Tachycardia Ectopic Atrial Tachycardia medicine.medical_specialty medicine.medical_treatment 030204 cardiovascular system & hematology Sensitivity and Specificity Article 03 medical and health sciences 0302 clinical medicine Monitoring Intraoperative Internal medicine Atrial Fibrillation Humans Medicine cardiovascular diseases 030212 general & internal medicine Atrial tachycardia Intracardiac Electrogram Fibrillation Fibrillatory conduction business.industry P wave Reproducibility of Results Electroencephalography Atrial fibrillation Middle Aged Ablation medicine.disease Treatment Outcome Anesthesia Catheter Ablation Disease Progression Cardiology Female medicine.symptom Electrophysiologic Techniques Cardiac Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Electrocardiology. 50:307-315 |
| ISSN: | 0022-0736 |
| DOI: | 10.1016/j.jelectrocard.2017.01.007 |
| Popis: | Background During ablation for atrial fibrillation (AF), it is challenging to anticipate transitions to organized tachycardia (AT). Defining indices of this transition may help to understand fibrillatory conduction and help track therapy. Objective To determine the timescale over which atrial fibrillation (AF) organizes en route to atrial tachycardia (AT) using the ECG referenced to intracardiac electrograms. Methods In 17 AF patients at ablation (58.7 ± 9.6 years; 53% persistent AF) we analyzed spatial loops of atrial activity on the ECG and intracardiac electrograms over successive timepoints. Loops were tracked at precisely 15, 10, 5, 3 and 1 min prior to defined transitions of AF to AT. Results Organizational indices reliably quantified changes from AF to AT. Spatiotemporal AF organization on the ECG was identifiable at least 15 min before AT was established (p = 0.02). Conclusions AF shows anticipatory global organization on the ECG minutes before AT is clinically evident. These results offer a foundation to establish when AF therapy is on an effective path, and for a quantitative classification separating AT from AF. |
| Databáze: | OpenAIRE |
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