Diagnostic utility of transbronchial biopsy for Hodgkin's lymphoma: A case study
| Autor: | Mai Matsumura, Hiroaki Fujii, Makiko Enaka, Katsushi Tanaka, Maki Hagihara, Ayami Kaneko, Keisuke Watanabe, Kohei Somekawa, Yoichi Tagami, Kenichi Seki, Yu Hara, Ami Izawa, Nobuyuki Horita, Nobuaki Kobayashi, Miki Hoshi, Ayako Aoki, Takeshi Kaneko |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Lung Neoplasms Biopsy Dacarbazine Case Report lymphoma Case Reports chemotherapy Positron Emission Tomography Computed Tomography Antineoplastic Combined Chemotherapy Protocols Bronchoscopy medicine Humans Brentuximab vedotin Lymph node RC254-282 Aged medicine.diagnostic_test business.industry Neoplasms. Tumors. Oncology. Including cancer and carcinogens General Medicine respiratory system Hodgkin's lymphoma medicine.disease Hodgkin Disease respiratory tract diseases Vinblastine Supraclavicular lymph nodes Lymphoma Radiography medicine.anatomical_structure Oncology Radiology business medicine.drug |
| Zdroj: | Thoracic Cancer Thoracic Cancer, Vol 12, Iss 23, Pp 3281-3285 (2021) |
| ISSN: | 1759-7714 1759-7706 |
| Popis: | Lung lesions of Hodgkin's lymphoma (HL) are rare and difficult to diagnose by nonsurgical biopsy. We herein present the case of a 72‐year‐old Japanese male who presented with accumulation of lung infiltrates and masses bilaterally on the lungs for 3 years. Although transbronchial lung biopsy (TBB) and computed tomography‐guided biopsy were conducted several times, his diagnosis remained inconclusive. On further deterioration of lung lesions, the patient was transferred to our hospital. Positron emission tomography revealed increased accumulation in the bilateral lungs and right supraclavicular lymph nodes. Surgical biopsy of the lymph node was performed. He was finally diagnosed with HL and underwent chemotherapy with doxorubicin, vinblastine, dacarbazine, and brentuximab vedotin. After chemotherapy, the lung lesion showed significant regression. A literature review indicated that the diagnostic success rate of TBB was low (18.5%) in cases of lung lesions in HL. Here, we report a case of undiagnosed HL with lung lesions despite multiple TBBs. Our literature review indicated that the diagnostic success rate of TBB was low (18.5%) in cases of lung lesions in HL. Surgical biopsy should be considered early to avoid a delay in diagnosis because the diagnostic ability of TBB for HL patients with lung lesions is limited. |
| Databáze: | OpenAIRE |
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