Panoply of Fluorescence Polarization/Anisotropy Signaling Mechanisms for Functional Nucleic Acid-Based Sensing Platforms
| Autor: | Sandrine Perrier, Benoit Chovelon, Corinne Ravelet, Valérie Guieu, Eric Peyrin |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Chemistry
010401 analytical chemistry Fluorescence Polarization 02 engineering and technology 021001 nanoscience & nanotechnology 01 natural sciences Small molecule 0104 chemical sciences Analytical Chemistry Feature (computer vision) Nucleic Acids Nucleic acid Biophysics Anisotropy 0210 nano-technology Fluorescence anisotropy Signal Transduction |
| Zdroj: | Analytical Chemistry. 90:4236-4248 |
| ISSN: | 1520-6882 0003-2700 |
| DOI: | 10.1021/acs.analchem.7b04593 |
| Popis: | Fluorescence polarization/anisotropy is a very popular technique that is widely used in homogeneous-phase immunoassays for the small molecule quantification. In the present Feature, we discuss how the potential of this signaling approach considerably expanded during the last 2 decades through the implementation of a myriad of original transducing strategies that use functional nucleic acid recognition elements as a promising alternative to antibodies. |
| Databáze: | OpenAIRE |
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