Alcoholic liver disease confers a worse prognosis than HCV infection and non-alcoholic fatty liver disease among patients with cirrhosis: An observational study
PLoS ONE PloS one, vol. 12, no. 10, pp. e0186715 PloS one, 12 (10 PloS one, Vol. 12, no. 10, p. e0186715 [1-16] (2017) PLoS ONE, Vol 12, Iss 10, p e0186715 (2017)
ISSN:
1932-6203
Popis:
Background: Cirrhosis is a heterogeneous clinical condition that includes patients at wide-ranging stages of severity. The role of the underlying liver disease on patient prognosis remains unclear. Aim: To assess the impact of the underlying liver disease on the occurrence of hepatocellular carcinoma (HCC) and death. Methods: Data related to the occurrence of HCC and death were collected during a 21-year period among patients with cirrhosis related to alcoholic liver disease (ALD) (n = 529), chronic hepatitis C virus (HCV) infection (n = 145) or non-alcoholic fatty liver disease (NAFLD) (n = 78). Results: At inclusion, ALD patients were younger than HCV and NAFLD patients (56 vs. 67 vs. 63 years; p SCOPUS: ar.j info:eu-repo/semantics/published