Prevalence of gonococcal conjunctivitis in adults and neonates
| Autor: | L McAnena, S. J. Knowles, L. Cassidy, A Curry |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Ophthalmia Neonatorum
Male medicine.medical_specialty Visual acuity Adolescent Gonorrhea Microbial Sensitivity Tests Hospitals Maternity medicine.disease_cause Hospitals Special Polymerase Chain Reaction Eye Infections Bacterial Neuro-ophthalmology Conjunctivitis Bacterial Young Adult Ciprofloxacin Internal medicine Prevalence Medicine Humans Young adult Child business.industry Ceftriaxone medicine.disease Neisseria gonorrhoeae Surgery Anti-Bacterial Agents Ophthalmology Child Preschool Clinical Study Female medicine.symptom business Ireland medicine.drug |
| Zdroj: | Eye (London, England). 29(7) |
| ISSN: | 1476-5454 |
| Popis: | Purpose To report the prevalence of gonococcal conjunctivitis (GC) presenting to a tertiary referral maternity hospital (NMH) and a tertiary referral ophthalmic hospital (RVEEH) from 2011 to 2013 and describe the demographics, clinical presentation, and antibiotic susceptibility of Neisseria gonorrhoeae ocular infections. Methods Demographic, clinical, and microbiological data were collected from patients with laboratory confirmed GC. Results There were 27 556 live births at NMH during the study period, and no case of neonatal GC was identified. Fourteen cases of GC were identified at RVEEH in this period, representing a prevalence of 0.19 cases per 1000 eye emergency attendees. Antibiotic susceptibility data were available on nine cases, of which, all were ceftriaxone- and ciprofloxacin sensitive. 64.3% of patients were male, with a mean age of 18 years. The mean duration of symptoms was 3 days. All patients presented with unilateral conjunctival injection and purulent discharge. Eight cases had visual impairment at presentation and their mean visual acuity was 6/15. Corneal involvement was present in 25% of patients. Uveitis was not detected. On receipt of positive culture and/or PCR results, treatment was altered in two thirds of patients. All patients were referred for full STI screening and all patients showed a full clinical recovery 1 week posttreatment. Conclusion We observed that GC presented in young adults with a male predominance and was rare in neonates. In cases of unilateral purulent conjunctivitis, there should be a high clinical suspicion of GC, early swab for PCR and culture, and knowledge of current CDC-recommended antibiotic guidelines. |
| Databáze: | OpenAIRE |
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