Consumption of vegetables and fruit and the risk of bladder cancer in the European Prospective Investigation into Cancer and Nutrition

Autor: Anne Tjønneland, Carlos González, Ole Raaschou-Nielsen, Marina Touillaud, Sabina Sieri, Françoise Clavel-Chapelon, Salvatore Panico, Lambertus A. Kiemeney, Jonas Manjer, Pagona Lagiou, Rudolf Kaaks, Dimitrios Trichopoulos, Nina Roswall, Andrew W. Roddam, Carla H. van Gils, Inger T. Gram, Steffen Weikert, Frederike L. Büchner, Kim Overvad, Paolo Vineis, Roy Ehrnström, Eva Ardanaz, Nadia Slimani, Martine M. Ros, H. Bas Bueno-de-Mesquita, Sheila Bingham, Traci Mouw, Eiliv Lund, Antonia Trichopoulou, Laudina Rodríguez, Göran Hallmans, Lars Egevad, Ellen Kampman, Rosario Tumino, Carmen Enid Martínez, Heiner Boeing, Kay-Tee Khaw, Marie-Christine Boutron-Ruault, Domenico Palli, Dagrun Engeset, Jenny Chang-Claude, Mazda Jenab, Dominique S. Michaud, Carmen Navarro, Naomi E. Allen, Petra H.M. Peeters, Nerea Larrañaga, Elio Riboli, Alina Vrieling, Börje Ljungberg, Paolo Boffetta
Přispěvatelé: Büchner, F.L., Bueno-De-Mesquita, H.B., Ros, M.M., Kampman, E., Egevad, L., Overvad, K., Raaschou-Nielsen, O., Tjønneland, A., Roswall, N., Clavel-Chapelon, F., Boutron-Ruault, M.-C., Touillaud, M., Chang-Claude, J., Kaaks, R., Boeing, H., Weikert, S., Trichopoulou, A., Lagiou, P., Trichopoulos, D., Palli, D., Sieri, S., Vineis, P., Tumino, R., Panico, S., Vrieling, A., Peeters, P.H.M., Van Gils, C.H., Lund, E., Gram, I.T., Engeset, D., Martinez, C., Gonzalez, C.A., Larrañaga, N., Ardanaz, E., Navarro, C., Rodríguez, L., Manjer, J., Ehrnström, R.A., Hallmans, G., Ljungberg, B., Allen, N.E., Roddam, A.W., Bingham, S., Khaw, K.-T., Slimani, N., Boffetta, P., Jenab, M., Mouw, T., Michaud, D.S., Kiemeney, L.A.L.M., Riboli, E., Büchner, Fl, Bueno de Mesquita, Hb, Ros, Mm, Kampman, E, Egevad, L, Overvad, K, Raaschou Nielsen, O, Tjønneland, A, Roswall, N, Clavel Chapelon, F, Boutron Ruault, Mc, Touillaud, M, Chang Claude, J, Kaaks, R, Boeing, H, Weikert, S, Trichopoulou, A, Lagiou, P, Trichopoulos, D, Palli, D, Sieri, S, Vineis, P, Tumino, R, Panico, Salvatore, Vrieling, A, Peeters, Ph, van Gils, Ch, Lund, E, Gram, It, Engeset, D, Martinez, C, Gonzalez, Ca, Larrañaga, N, Ardanaz, E, Navarro, C, Rodríguez, L, Manjer, J, Ehrnström, Ra, Hallmans, G, Ljungberg, B, Allen, Ne, Roddam, Aw, Bingham, S, Khaw, Kt, Slimani, N, Boffetta, P, Jenab, M, Mouw, T, Michaud, D, Kiemeney, La
Rok vydání: 2009
Předmět:
Male
Cancer Research
Nutrition and Disease
Aetiology
screening and detection [ONCOL 5]
Cohort Studies
0302 clinical medicine
Risk Factors
Voeding en Ziekte
Vegetables
Epidemiology
Prospective Studies
030212 general & internal medicine
Prospective cohort study
2. Zero hunger
carotenoids
Middle Aged
3. Good health
European Prospective Investigation into Cancer and Nutrition
Oncology
030220 oncology & carcinogenesis
Female
epidemiology
vitamin-c
Cohort study
Adult
medicine.medical_specialty
prospective cohort
consumption vegetables fruit risk bladder cancer European Prospective Investigation Cancer Nutrition
folate
Molecular epidemiology [NCEBP 1]
03 medical and health sciences
Translational research [ONCOL 3]
Environmental health
medicine
Humans
Risk factor
Aged
VLAG
Consumption (economics)
Gynecology
Bladder cancer
Hereditary cancer and cancer-related syndromes [ONCOL 1]
cigarette-smoking
business.industry
food
Cancer
medicine.disease
Urinary Bladder Neoplasms
Fruit
diet
business
Follow-Up Studies
Zdroj: International Journal of Cancer, 125, 11, pp. 2643-51
Büchner, F L, Bueno-de-Mesquita, H B, Ros, M M, Kampman, E, Egevad, L, Overvad, K, Raaschou-Nielsen, O, Tjønneland, A, Roswall, N, Clavel-Chapelon, F, Boutron-Ruault, M-C, Touillaud, M, Chang-Claude, J, Kaaks, R, Boeing, H, Weikert, S, Trichopoulou, A, Lagiou, P, Trichopoulos, D, Palli, D, Sieri, S, Vineis, P, Tumino, R, Panico, S, Vrieling, A, Peeters, P H M, van Gils, C H, Lund, E, Gram, I T, Engeset, D, Martinez, C, Gonzalez, C A, Larrañaga, N, Ardanaz, E, Navarro, C, Rodríguez, L, Manjer, J, Ehrnström, R A, Hallmans, G, Ljungberg, B, Allen, N E, Roddam, A W, Bingham, S, Khaw, K-T, Slimani, N, Boffetta, P, Jenab, M, Mouw, T, Michaud, D S, Kiemeney, L A L M & Riboli, E 2009, ' Consumption of vegetables and fruit and the risk of bladder cancer in the European Prospective Investigation into Cancer and Nutrition ', International Journal of Cancer, vol. 125, no. 11, pp. 2643-51 . https://doi.org/10.1002/ijc.24582
International Journal of Cancer, 125(11), 2643-2651
International Journal of Cancer 125 (2009) 11
International Journal of Cancer, 125, 2643-51
ISSN: 1097-0215
0020-7136
Popis: Contains fulltext : 81056.pdf (Publisher’s version ) (Closed access) Previous epidemiologic studies found inconsistent associations between vegetables and fruit consumption and the risk of bladder cancer. We therefore investigated the association between vegetable and fruit consumption and the risk of bladder cancer among participants of the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Data on food consumption and complete follow-up for cancer occurrence was available for a total of 478,533 participants, who were recruited in 10 European countries. Estimates of rate ratios were obtained by Cox proportional hazard models, stratified by age at recruitment, gender and study centre, and adjusted for total energy intake, smoking status, duration of smoking and lifetime intensity of smoking. A calibration study in a subsample was used to control for dietary measurement errors. After a mean follow-up of 8.7 years, 1015 participants were newly diagnosed with bladder cancer. Increments of 100 g/day in fruit and vegetable consumption combined did not affect bladder cancer risk (i.e., calibrated HR = 0.98; 95%CI: 0.95-1.01). Borderline statistically significant lower bladder cancer risks were found among never smokers with increased consumption of fruit and vegetables combined (HR = 0.94 95%CI: 0.87-1.00 with increments of 100 g/day; calibrated HR = 0.92 95%CI 0.79-1.06) and increased consumption of apples and pears (hard fruit; calibrated HR = 0.90 95%CI: 0.82-0.98 with increments of 25 g/day). For none of the associations a statistically significant interaction with smoking status was found. Our findings do not support an effect of fruit and vegetable consumption, combined or separately, on bladder cancer risk.
Databáze: OpenAIRE
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