Oral Ulcers in Juvenile-Onset Systemic Lupus Erythematosus: A Review of the Literature
| Autor: | Michael W. Beresford, Steven W. Edwards, Tawatchai Deekajorndech, Pongsawat Rodsaward, Direkrit Chiewchengchol, Titipong Prueksrisakul |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Review Article Dermatology Disease Systemic therapy 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Pharmacotherapy Biopsy medicine Humans Lupus Erythematosus Systemic Age of Onset Oral ulcers Child skin and connective tissue diseases Oral Ulcer 030203 arthritis & rheumatology Lupus erythematosus medicine.diagnostic_test business.industry General Medicine medicine.disease digestive system diseases stomatognathic diseases Juvenile onset Female Age of onset business |
| Zdroj: | American Journal of Clinical Dermatology AMERICAN JOURNAL OF CLINICAL DERMATOLOGY |
| ISSN: | 1179-1888 1175-0561 |
| DOI: | 10.1007/s40257-017-0286-9 |
| Popis: | Oral ulcers are the most common mucosal sign in juvenile-onset systemic lupus erythematosus (JSLE). The ulcers are one of the key clinical features; however, the terminology of oral ulcers, especially in JSLE patients, is often vague and ill-defined. In fact, there are several clinical manifestations of oral ulcers in JSLE, and some lesions occur when the disease is active, indicating that early management of the disease should be started. Oral ulcers are classified as lupus erythematosus (LE) specific, where the lesional biopsy shows a unique pattern of mucosal change in LE, and LE nonspecific, where the ulcers and their histopathological findings can be found in other oral diseases. Here, the clinical manifestations, diagnosis and management of oral ulcers in JSLE patients are reviewed. |
| Databáze: | OpenAIRE |
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