Tissue Proteases and Immune Responses: Influencing Factors of COVID-19 Severity and Mortality
| Autor: | Maria Fernanda de Paula Werner, Laryssa Regis Bueno, Claudia Rita Corso, Karien Sauruk da Silva, Bruna Barbosa da Luz, Daniele Maria-Ferreira, Elizabeth S. Fernandes, Natalia Mulinari Turin de Oliveira, Liziane Cristine Malaquias da Silva, Isabella Fernandes da Silva Figueiredo |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Microbiology (medical)
Proteases Population lcsh:Medicine Disease Review medicine.disease_cause Immune system Diabetes mellitus medicine Immunology and Allergy education Molecular Biology Coronavirus Asthma education.field_of_study General Immunology and Microbiology disease outcome business.industry SARS-CoV-2 Incidence (epidemiology) lcsh:R COVID-19 medicine.disease host factors immune responses tissue proteases Infectious Diseases Immunology business |
| Zdroj: | Pathogens Pathogens, Vol 9, Iss 817, p 817 (2020) |
| ISSN: | 2076-0817 |
| Popis: | The coronavirus disease 19 (COVID-19) is caused by the highly transmissible severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has affected the global population despite socioeconomic status and amazed surveillance agencies for its incidence, mortality, and recovery rates. COVID-19 affects all age groups; however, it is suggested to progress into severe disease and cause mortality in over 10% of the confirmed cases, depending on the individual characteristics of the affected population. One of the biggest unanswered questions it is why only some individuals develop into the severe stages of the disease. Current data indicate that most of the critically ill are the elderly or those with comorbidities such as hypertension, diabetes, and asthma. However, it has been noted that, in some populations, severe disease is mostly observed in much younger individuals ( |
| Databáze: | OpenAIRE |
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