Outcome of truncus arteriosus repair: 20 years of single-center experience comparing early versus late surgical repair
| Autor: | Fahad Alhabshan, Riyadh Abu-Sulaiman, Mohammed H. A. Mohammed, Muna Ismail, Abdah Hrfi, Hussam K. Hamadah, Mohamed S. Kabbani |
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| Rok vydání: | 2021 |
| Předmět: |
Heart Defects
Congenital Reoperation congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Truncus Arteriosus Hypertension Pulmonary Persistent truncus arteriosus Single Center Cohort Studies medicine Humans Child Surgical repair business.industry Persistent pulmonary hypertension Infant Newborn Infant General Medicine Early infancy medicine.disease Pulmonary hypertension Truncus Arteriosus Persistent Surgery Treatment Outcome Pediatrics Perinatology and Child Health Cardiology and Cardiovascular Medicine business Cohort study Follow-Up Studies |
| Zdroj: | Cardiology in the young. 32(8) |
| ISSN: | 1467-1107 1047-9511 |
| Popis: | Background:Truncus arteriosus is a rare CHD. Neonatal and early infancy repair is recommended though some cases may present late. The aim of our study is to investigate the current results of truncus arteriosus repair and to analyse the differences in outcome and reintervention need between early versus late truncus arteriosus surgical repair.Material and methods:In this cohort study, we reviewed all children who underwent truncus arteriosus repair from 2001 till 2021. We divided patients into two groups; early repair group including patients repaired at age less than 3 months and late repair group including patients who had repair at 3 months of age and later. We compared both groups for outcome variables.Results:Sixty-four children had truncus arteriosus repair including 48(75%) patients in early repair and 16(25%) patients in late repair groups. Peri-operative course was comparable between both groups. Post-surgery, we observed pulmonary hypertension in 6(12%) patients in early repair group comparing with 11(69%) patients in late repair group (p = 0.0001). In the last follow-up visit, pulmonary hypertension resolved in all early repair group patients while 6(37.5%) patients in late repair group continued to have pulmonary hypertension (p = 0.0001). Twenty-three(36%) patients required reintervention including 22(48%) in early repair group versus 1(6%) in late repair group (p = 0.007).Conclusion:In general, the outcome of early truncus arteriosus repair is excellent with resolution of pulmonary hypertension following early repair. Late repair caries higher risk of persistent pulmonary hypertension (37.5%). About one-third of the patients who had truncus arteriosus repair will require re-intervention within 38±38.4 months after initial surgery. |
| Databáze: | OpenAIRE |
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