Genetic and genomic analysis of oxygen consumption in mice

Autor:	Shinichiro Ogawa, Hongyu Darhan, Keiichi Suzuki
Rok vydání:	2022
Předmět:	Mice Genome Oxygen Consumption Food Animals Body Weight Animals Animal Science and Zoology Genomics General Medicine
Zdroj:	Journal of Animal Breeding and Genetics. 139:596-610
ISSN:	1439-0388 0931-2668
DOI:	10.1111/jbg.12721
Popis:	We estimated genetic parameters of oxygen consumption (OC), OC per metabolic body weight (OCMBW), and body weight at three through eight weeks of age in divergently selected mice populations, with an animal model considering maternal genetic, common litter environmental, and cytoplasmic inheritance effects. Cytoplasmic inheritance was considered based on maternal lineage information. For OC, estimated direct heritability was moderate (0.32) and estimated maternal heritability and proportion of the variance of cytoplasmic inheritance effects to the phenotypic variance were very low (both Ndufa12, Sdhc, Atp10b, etc.),Prr16encoding Largen protein,Cry1encoding a key component of the circadian core oscillator, and so on. The results could contribute to elucidate the genetic mechanism of OC, an indicator for maintenance energy requirement and therefore feed efficiency.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4cc3650b365d0dcdf5c330d1966e07 https://doi.org/10.1111/jbg.12721 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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