Early Detection of Chronic Asymptomatic Chagas Infection
| Autor: | Ezequiel de la Rosa, Laura Beatriz Prato, María Fernanda Triquell, Sonia E. Muñoz, Patricia Paglini-Oliva, Evangelina Benizio, Elmer Andrés Fernández |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Chagas disease
medicine.medical_specialty Blood transfusion medicine.medical_treatment 0206 medical engineering Early detection INGENIERÍAS Y TECNOLOGÍAS 02 engineering and technology Disease Asymptomatic Organ transplantation Electrocardiography Epidemiology 0202 electrical engineering electronic engineering information engineering medicine Humans Mass Screening Chagas Disease Tecnología de Laboratorios Médicos Intensive care medicine Review Articles Ingeniería Médica Mass screening business.industry CHAGAS DISEASE General Medicine medicine.disease 020601 biomedical engineering Early Diagnosis MASS SCREENING 020201 artificial intelligence & image processing Public Health PUBLIC HEALTH medicine.symptom business ELECTROCARDIOGRAPHY |
| Zdroj: | Medical Science Monitor : International Medical Journal of Experimental and Clinical Research |
| ISSN: | 1643-3750 |
| DOI: | 10.12659/msm.907735 |
| Popis: | Chagas disease, also known as American trypanosomiasis, is a chronic and systemic parasitic infection which has become a serious epidemiological problem not only in endemic regions (Latin America), but also in nonendemic ones like North America, Europe, and Oceania. Subjects with the indeterminate chagasic form (ICF), a chronic asymptomatic disease stage, are the main sources of non-vectorial dissemination through blood transfusion, organ transplantation, and congenital transmission. It has been suggested that 94% of urban infections can be explained by these subjects. Under this scenario, the availability of simple and effective screening methods for ICF detection becomes crucial for both prevention of disease propagation and detection of clinical stages. Recently, a new non-invasive method has been proposed for ICF detection. It is based on surface high-resolution ECG and it could be easily adopted and included in modern ECG devices, overcoming the limitations of serological-based tests. The proposed method shows accuracy for early ICF screening, thus improving prognosis by defining the clinical stages and allowing appropriate and effective treatment. Fil: de la Rosa, Ezequiel. Universidad de Girona; España Fil: Paglini Oliva, Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina Fil: Prato, Laura Beatriz. Universidad Nacional de Villa María. Instituto Académico Pedagógico de Ciencias Básicas y Aplicadas; Argentina Fil: Triquell, María Fernanda. Universidad Nacional de Córdoba. Facultad de Medicina. Cátedra de Histología,embriología y Genética I; Argentina Fil: Benizio, Evangelina Leticia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina Fil: Muñoz, Sonia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina Fil: Fernandez, Elmer Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigación y Desarrollo en Inmunología y Enfermedades Infecciosas. Universidad Católica de Córdoba. Centro de Investigación y Desarrollo en Inmunología y Enfermedades Infecciosas; Argentina |
| Databáze: | OpenAIRE |
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