Effective factors on Sharp Score in patients with rheumatoid arthritis: a retrospective study
Autor: | Yue Sun, Lei Wan, Xin Wang, Hui Jiang, Jie Wang, Ling Xin, Jian Liu, Jianting Wen, Yanqiu Sun |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Male
medicine.medical_specialty Sports medicine Blood Sedimentation Diseases of the musculoskeletal system Logistic regression Severity of Illness Index Arthritis Rheumatoid Rheumatology Rheumatoid Factor Internal medicine Epidemiology Medicine Rheumatoid factor Humans Orthopedics and Sports Medicine Rheumatoid arthritis Retrospective Studies medicine.diagnostic_test business.industry Effective factors Retrospective cohort study Middle Aged medicine.disease Sharp score Retrospective study RC925-935 Erythrocyte sedimentation rate Female business Research Article |
Zdroj: | BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-8 (2021) BMC Musculoskeletal Disorders |
ISSN: | 1471-2474 |
Popis: | Background This study aims to describe the association between sharp score and clinical indexes, bone metabolism indexes, Disease Activity Score (DAS28) and sociodemographic factors in rheumatoid arthritis (RA). Methods Data were collected from the HIS (hospital information system), a national inpatient database in China, with information on the patients hospitalized during the period from 2012 to 2019. The association between sharp score and effective factors were identified using multinomial logistic regression and association rule mining (ARM). Results Three thousand eight hundred and forty patients were included: 82.66% males, 17.34% females, mean (SD) age 56.95 (12.68) years and symptom duration 3.45 (1.09) years. Spearman correlation analysis and Association rules analysis showed that there were significant positive correlations between sharp score and effective factors. Logistic regression analysis presented that erythrocyte sedimentation rate (ESR), high-sensitivity C-reactive protein (CRP), rheumatoid factor (RF) were risk factors of sharp score. In the analysis of individual outcomes, sex, age, symptom duration, DSA28 score, RF, ever drinker, and radiographic grading of hands were influence factors of sharp score. Conclusion Sharp score should be taken into consideration in formulating treatment strategies in RA. |
Databáze: | OpenAIRE |
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