Management following heart and lung transplantation: five years experience
Autor: | John P. Scott, T. W. Higenbottam, R L Smyth, G. Fradet, E. Solis, John Wallwork |
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Rok vydání: | 1990 |
Předmět: |
Graft Rejection
Lung Diseases Pulmonary and Respiratory Medicine medicine.medical_specialty Heart-Lung Transplantation Biopsy medicine.medical_treatment Congenital cytomegalovirus infection Pneumocystis pneumonia Postoperative Complications medicine Humans Lung transplantation Cardiopulmonary disease Pneumonitis Postoperative Care Lung business.industry Respiratory disease General Medicine medicine.disease Surgery Transplantation medicine.anatomical_structure Cytomegalovirus Infections Cardiology and Cardiovascular Medicine business |
Zdroj: | European Journal of Cardio-Thoracic Surgery. 4:197-201 |
ISSN: | 1010-7940 |
DOI: | 10.1016/1010-7940(90)90004-j |
Popis: | Since April 1984, 70 patients have received heart-lung transplants at our institution. Actuarial survival is 76% at 1 year and 68% at 2 years. All but 4 surviving patients have an unrestricted life style. Rejection was confirmed by lung transbronchial biopsy (TBB) on 277 occasions in 66 patients. Forty-two percent of episodes occurred within 1 month of surgery. Eight patients have developed evidence of chronic rejection with progressive irreversible fall in FEV1, of whom 4 have died or undergone single lung retransplantation. Seven patients had primary cytomegalovirus (CMV) of whom 4 patients died. Eight patients developed pneumocystis pneumonia of whom 1 died. Seven episodes of herpes simplex pneumonitis occurred of which one episode was fatal. Heart-lung transplantation is a valuable treatment for terminal cardiopulmonary disease and offers increasing hope of long-term survival. |
Databáze: | OpenAIRE |
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