Clostridium Sordelliias an Uncommon Cause of Fatal Toxic Shock Syndrome in a Postpartum 33-Year-Old Asian Woman, and the Need for Antepartum Screening for This Clostridia Species in the General Female Population
| Autor: | Scott Duong, Melissa Guzzetta, Alex K. Williamson |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
0301 basic medicine medicine.medical_specialty 030106 microbiology Clinical Biochemistry Clostridium sordellii Biology Abortion Microbiology 03 medical and health sciences Case Studies Fatal Outcome 0302 clinical medicine Asian People medicine Humans Mass Screening Childbirth 030212 general & internal medicine Mass screening Bacteriological Techniques Septic shock Obstetrics Postpartum Period Biochemistry (medical) Toxic shock syndrome Prenatal Care medicine.disease biology.organism_classification Shock Septic medicine.anatomical_structure Spectrometry Mass Matrix-Assisted Laser Desorption-Ionization Clostridium Infections Vagina Female Postpartum period |
| Zdroj: | Laboratory Medicine. 47:251-254 |
| ISSN: | 1943-7730 0007-5027 |
| DOI: | 10.1093/labmed/lmw025 |
| Popis: | Clostridium sordellii (C. sordellii) is an anaerobic gram-positive rod most commonly found in the soil and sewage but also as part of the normal flora of the gastrointestinal tract and vagina of a small percentage of healthy individuals. C. sordellii infection is considered to result from childbirth, abortion, and/or gynecological procedures. Although many strains of C. sordellii are nonpathogenic, virulent toxin-producing strains exist. Infection with this organism typically manifests as a patient experiencing septic shock rapidly followed by end-organ failure. Identification of C. sordelli has been successful by traditional culture, mass spectrometry methods, and via molecular methods. Herein, we present a fatal case of C. sordellii infection of a postpartum 33-year-old Asian woman. The organism was isolated by culture and identified using matrix-assisted laser desorption/ionization-time-of-flight (MALDI-TOF) technology. With the advent of rapid detection methods, antepartum screening for the fatal Clostridium species should be implemented in the general female population. |
| Databáze: | OpenAIRE |
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